Increased drug resistance associated with reduced glucose levels and an enhanced glycolysis phenotype (Br J of Pharmacology, July 2014)


Increased drug resistance associated with reduced glucose levels and an enhanced glycolysis phenotype (Br J of Pharmacology, July 2014) Drug testing in-vitro has traditionally been performed in hyperglycemic cell culture concentrations, yet many tumours and their microenvironments...

READ MORE

A Role for RUNX3 in Inflammation-Induced Expression of IL23A in Gastric Epithelial Cells (Cell Reports, July 2014)


A Role for RUNX3 in Inflammation-Induced Expression of IL23A in Gastric Epithelial Cells (Cell Reports, July 2014) RUNX3 functions as a tumor suppressor in the gastric epithelium, where its inactivation is frequently observed during carcinogenesis. We...

READ MORE

LEO1 Is Regulated by PRL-3 and Mediates Its Oncogenic Properties in Acute Myelogenous Leukemia (Cancer Res, June 2014)


LEO1 Is Regulated by PRL-3 and Mediates Its Oncogenic Properties in Acute Myelogenous Leukemia (Cancer Res, June 2014) PRL-3, an oncogenic dual-specificity phosphatase, is overexpressed in 50% of acute myelogenous leukemia (AML) and associated with poor survival. We...

READ MORE