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Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma (Nat Genet, Aug 2014)


Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma (Nat Genet, Aug 2014) Fibroadenomas are the most common breast tumors in women under 30 (refs. 1,2). Exome sequencing of eight fibroadenomas with matching whole-blood...

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DEAD-box Helicase DP103 Defines Metastatic Potential of Human Breast Cancers (J Clin Invest, Aug 2014)


DEAD-box Helicase DP103 Defines Metastatic Potential of Human Breast Cancers (J Clin Invest, Aug 2014) Despite advancement in breast cancer treatment, 30% patients with early breast cancers experience relapse with distant metastasis. Therefore, there...

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Increased drug resistance associated with reduced glucose levels and an enhanced glycolysis phenotype (Br J of Pharmacology, July 2014)


Increased drug resistance associated with reduced glucose levels and an enhanced glycolysis phenotype (Br J of Pharmacology, July 2014) Drug testing in-vitro has traditionally been performed in hyperglycemic cell culture concentrations, yet many tumours and their microenvironments...

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