Bing ZHU

Institute of Biophysics, Chinese Academy of Sciences

Bing Zhu, Ph.D., Investigator, Deputy Director, Institute of Biophysics, Chinese Academy of Sciences, is interested in the establishment and maintenance of epigenetic modifications. Dr. Zhu received his Bachelor degree in Zhejiang University (1992), Ph.D. in Shanghai Institute of Plant Physiology, Chinese Academy of Sciences (1999). Dr. Zhu received his postdoc training in Friedrich Miescher Institute, Switzerland (1999-2002) and Howard Hughes Medical Institute, USA (2002-2006). Dr. Zhu established his own research lab in the National Institute of Biological Sciences, Beijing in 2006 and joined the Institute of Biophysics, Chinese Academy of Science in 2014. Dr. Zhu is an awardee of International Early Career Scientist of the Howard Hughes Medical Institute. Dr. Zhu is an editorial board member of J. Biol. Chem. and EMBO Rep.

Zhu lab clarified the nucleosome partition patter during mitotic division (Science 2010), discovered the role of dense chromatin in activating histone H3K27-specific methyltransferase complex PRC2 and illustrated its functional significance in mitotic inheritance of histone modifications (Science 2012). More recently, Zhu lab discovered an active mechanism mediated by Stella in safeguarding the de novo methylation establishment process during oogenesis and revealed an unexpected role of DNMT1 in de novo methylation (Nature 2018).