Dr. Clotilde Théry is an INSERM director of research (DR1) working at Institut Curie, where she heads the team “Extracellular Vesicles, Immune responses and Cancer”.
Before joining Institut Curie as a post-doctoral researcher in 1996 to work on the cell biology of antigen presentation, she had been studying development of the brain for her PhD in Paris, and a post-doc in Oxford University UK, then Columbia University, New York USA.
Since 1998, her scientific interests have focused on the study of exosomes (and more recently extracellular vesicles in general), secreted by immune and tumor cells, and their roles in communications between tumors and the immune system. Her goals are to understand the physiological functions of EV secretion during an in vivo immune response and during tumor growth, and her approach is to continuously go from basic cell biology questions on their modes of formation to application of this knowledge to in vivo situations.
C. Théry is regularly invited to write reviews on the subject of exosomes, EVs, their immune functions and their biogenesis. She has organized several symposia and sessions dedicated to exosomes in international meetings, and in particular a first “International Workshop on Exosomes” in Institut Curie, in Paris, in 2011, which led to the creation of the International Society for Extracellular Vesicles (ISEV), for which she served as Secretary General from 2012 to 2016, and more recently President (2020-2022). She has been Editor in Chief of the journal of the Society, J Extracell Vesicles, from its creation in 2012 until 2019. In addition to publishing numerous highly cited original articles and reviews, she has led the community-based efforts to standardization and reproducibility of EV research, which resulted in the MISEV2018 guideline article (Théry*, Witwer* et al, J Extracell Vesicles 2018). She has been listed “highly cited researcher” by Clarivate in 2019 and 2020.