Dorothy A. SIPKINS

Duke University, USA

Dr. Sipkins has been an Associate Professor at Duke University in the Dept. of Medicine, Division of Hematologic Malignancies and Cellular Therapy, since 2014. Prior to that, she was an Assistant Professor at the University of Chicago.  She received her MD and PhD from Stanford University and was a resident and fellow at Massachusetts General Hospital and Dana-Farber Cancer Institute.  She currently attends on the inpatient hematologic malignancy service at Duke University Hospital.  Her clinical area of interest is leukemia and bone marrow failure disorders. In her research laboratory, she studies the role of the bone marrow microenvironment in regulating the growth of leukemia and breast cancer metastases. Her major research focus is in understanding how cancer progression is regulated by specific interactions with the host microenvironment that control tumor behaviors ranging from migration to dormancy and chemo-resistance. To accomplish this, the Sipkins lab utilizes real-time, single cell resolution assays including intravital confocal and dual photon microscopy to study these processes in mouse models. Dr. Sipkins is actively developing early phase clinical trials to test the lab’s pre-clinical findings in patient populations and further investigate these molecular mechanisms in humans.