Cancer Science Institute of Singapore
Dr Polly Leilei Chen got her Bachelor of Medicine in 2002 from Medical school, Jiangsu University, China, followed by 2-year specialized training in Obstetrics & Gynecology. She completed her PhD in Cancer Genetics in Prof. Xin-Yuan Guan’s laboratory at the University of Hong Kong in 2010. After 2-year postdoctoral training in the same lab, she joined Cancer Science Institute of Singapore as a Special fellow in 2012, and was promoted to a Principle Investigator and joined the Department of Anatomy, NUS, as an Assistant professor in 2014. She was recently inducted into the Prestigious EMBO Young Investigator Programme.
Dr. Chen’s research has centered on transcriptome alterations in human cancers and in particular on understanding how A-to-I RNA editing contributes to cancer initiation and progression. She currently places focus on the regulators of A-to-I RNA editing, the crosstalk between RNA editing and other RNA processes, and the development of RNA-based therapeutics targeting cancer-driven editing events.