FENG Gen Sheng

University of California San Diego, USA

Dr. Gen-Sheng Feng is a Professor of Pathology and Molecular Biology at the University of California San Diego (UCSD). He received his B.Sc. degree in Biology from Hangzhou University, M.Sc. degree in Immunology from 2nd Medical University of Army in Shanghai, and PhD in Molecular Biology from Indiana University Bloomington. Dr. Feng did a postdoctoral fellowship at the University of Toronto, Canada. Dr. Feng serves on editorial boards for MCB, Hepatology and Journal of Hepatology, etc. and is a fellow of American Association for Advancement of Science (AAAS).

Dr. Feng is a Co-Director of the Primary Liver Cancer Task Force of the Moores UCSD Cancer Center. Dr. Feng’s research aims at understanding the intertwining of signaling pathways in health and diseases, by focusing on tyrosine phosphatase Shp2 that he discovered during postdoc studies. His most recent work has uncovered pro- and anti-tumorigenic roles of Shp2 in hepatic and blood malignancies, and the current interests are in delineating molecular and cellular mechanisms that drive liver tumor initiation, in isolating and characterizing liver tumor-initiating cells, and in dissecting the dynamic interplay between tumors and the hepatic microenvironment. The goal is to elucidate the anti-oncogenic effects of the classical oncoproteins in liver cancer, which will lead to development of better diagnostic and therapeutic recipes.