Duke-NUS Medical School

Dr. Itahana obtained B.S. and Ph.D. degree at the Faculty of Science, Kyoto University in Japan. He subsequently received the postdoctoral training at the laboratory of Dr. Judith Campisi, Lawrence Berkeley National Laboratory to study the role of p53 in cellular senescence and the laboratory of Dr. Yanping Zhang, University of North Carolina at Chapel Hill to study the role of ARF-Mdm2-p53 pathway in tumor suppression. After he started his own laboratory at Cancer & Stem Cell Biology Program, Duke-NUS Medical School in Oct, 2009, he has isolated numbers of targets and modulators of ARF-Mdm2-p53 pathway to reveal several novel non-canonical functions of ARF-Mdm2-p53 pathway in preventing tumorigenesis. He is currently an Associate Professor at Duke-NUS Medical School, and continues to work on the functions of ARF and p53. He also studies the role of p53 pathway and PP2A in cancer metabolism.