Yvonne TAY

Cancer Science Institute of Singapore, NUS

Yvonne began her research career in Bing Lim’s lab at the Genome Institute of Singapore, supported by an A*STAR Graduate Scholarship, and her PhD work led to key insights into the scope and mechanisms of microRNA activity (Miranda et al, Cell 2006; Tay et al, Nature 2008). Subsequently, she pursued her postdoctoral training in Pier Paolo Pandolfi’s lab at Harvard Medical School and Beth Israel Deaconess Medical Center under a Special Fellow award from the Leukemia & Lymphoma Society, and this research led to the discovery that protein-coding transcripts can co-regulate the tumor suppressor PTEN by competing for shared microRNAs (Tay et al, Cell 2011; Karreth et al, Cell 2011). Yvonne has recently returned to Singapore to begin her independent research career, and has been awarded the Singapore National Research Foundation Fellowship and NUS President’s Assistant Professorship to continue her research into this previously uncharacterized layer of gene regulation.