Stanford University, USA

Karlene Cimprich received a B.S. in Chemistry from the University of Notre Dame, and a Ph.D. in Chemistry from Harvard University. She then completed a Damon Runyon-Walter Winchell postdoctoral fellowship with Stuart Schreiber at Harvard University. She joined the faculty in the Department of Chemical and Systems Biology at Stanford University in 1998, was tenured in 2006, and promoted to full Professor in 2013. Dr. Cimprich has studied many aspects of genome instability, particularly as it relates to DNA replication stress. She has studied DNA damage signaling pathways with an emphasis on the ATR kinase, as well as DNA damage tolerance pathways. More recently her lab has also studied genome instability resulting from R-loop formation and interactions between replication and transcription. Her work uses a broad range of methodologies, including biochemistry, cell biology and omics technologies, and she has used both mammalian cell culture and cell free extracts as model systems. Dr. Cimprich is a member of the editorial boards of Molecular Cell, Journal of Cell Biology and Cell Reports, and she has also co-organized several conferences, including Keystone, Cold Spring Harbor and Gordon Conferences. Finally, Dr. Cimprich has been recognized with several awards, including the Kimmel Scholar Award, Beckman Scholar Award, Burroughs Wellcome New Investigator Award in Toxicology, Leukemia and Lymphoma Scholar Award, Ellison Senior Scholar Award and most recently as a AAAS Fellow.