Novel Research Paves Way for Better Optimization of Daratumumab Treatment for NK/T lymphoma Patients

September 9, 2021

Natural Killer T cell lymphoma (NKTL) is a highly aggressive form of cancer more frequently occurring in Asia than other...

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Sep 09, 2021 Celine Tam 0 comments
Sep 07, 2021 Celine Tam 0 comments
Virtual Graduation Celebration for the Graduating Classes of 2020 and 2021

September 3, 2021

Congratulations to the graduates of the PhD Graduate Program in Cancer Biology! On 27th August 2021, CSI Singapore organized a...

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Sep 03, 2021 Celine Tam 0 comments
Determinants of Response to Daratumumab in Epstein-Barr Virus-Positive Natural Killer and T-Cell Lymphoma. (J Immunother Cancer, Jul 2021)

August 31, 2021

This study characterizes CD38 as an effective target for a subset of NKTL patients and the utilization of the CD38:CIP...

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Aug 31, 2021 Celine Tam 0 comments
Chromatin Interaction Neural Network (ChINN): A Machine Learning-Based Method for Predicting Chromatin Interactions from DNA Sequences. (Genome Biol, Aug 2021)

August 31, 2021

Chromatin interactions play important roles in regulating gene expression. However, the availability of genome-wide chromatin interaction data is limited. We...

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Aug 31, 2021 Celine Tam 0 comments
Repurposing RNA Sequencing for Discovery of RNA Modifications in Clinical Cohorts. (Sci Adv, Aug 2021)

August 31, 2021

The study of RNA modifications in large clinical cohorts can reveal relationships between the epitranscriptome and human diseases, although this...

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Aug 31, 2021 Celine Tam 0 comments
CSI Director Shares His Thoughts on Building a Great and Inclusive Workplace

August 23, 2021

CSI Singapore Director, Prof. Ashok Venkitaraman, recently shared his experiences and aspirations for inclusive and equitable policies and practices in...

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Aug 23, 2021 Celine Tam 0 comments
CSI Singapore Receives NUS Safety & Health Commendation Award

August 6, 2021

We are pleased to announce that CSI Singapore has been conferred the Commendation Award for the NUS Safety & Health...

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Aug 06, 2021 Celine Tam 0 comments
CSI Singapore Conferred Multiple Awards at NCIS Annual Research Meeting (NCAM 2021)

August 4, 2021

Hosted by the National University Cancer Institute, Singapore (NCIS) and co-organized by the Cancer Science Institute of Singapore (CSI), the...

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Aug 04, 2021 Celine Tam 0 comments
Researchers Discover a New Link Between Oxidative Stress and Ageing-Related Human Diseases

August 4, 2021

Our bodies constantly encounter oxidants from our diet and metabolism. Oxidative stress is thought to speed up ageing, and increase...

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Aug 04, 2021 Celine Tam 0 comments
Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation. (Genome Biol, Jun 2021)

July 6, 2021

CIMP (CpG island methylator phenotype) is an epigenetic molecular subtype, observed in multiple malignancies and associated with the epigenetic silencing...

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Jul 06, 2021 Celine Tam 0 comments
Mitochondria transfer from early stages of erythroblasts to their macrophage niche via tunnelling nanotubes. (Br J Haematol, Jun 2021)

July 6, 2021

Adult erythropoiesis entails a series of well-coordinated events that produce mature red blood cells. One of such events is the...

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Jul 06, 2021 Celine Tam 0 comments
SMARCA2 Is a Novel Interactor of NSD2 and Regulates Prometastatic PTP4A3 through Chromatin Remodeling in t(4;14) Multiple Myeloma. (Cancer Res, May 2021)

July 6, 2021

NSD2 is the primary oncogenic driver in t(4;14) multiple myeloma. Using SILAC-based mass spectrometry, we demonstrate a novel role of...

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Jul 06, 2021 Celine Tam 0 comments
Researchers Identify Looping Silencers as a Promising Target for Cancer Treatment

June 17, 2021

Gene transcription is controlled largely by transcription factors that bind to enhancers, which are regions of the DNA that loop...

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Jun 17, 2021 Celine Tam 0 comments
Prof. Chng Wee Joo Receives Yong Loo Lin School of Medicine Graduate Mentor of the Year (GRAMAY) Award 2021

June 10, 2021

Congratulations to CSI Deputy Director and Senior Principal Investigator, Prof. Chng Wee Joo, on being conferred the Yong Loo Lin...

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Jun 10, 2021 Celine Tam 0 comments
A Novel Discovery Platform to Identify First-in-Class Druggable Targets for Human Diseases

June 10, 2021

Protein-protein interactions (PPIs) represent a vast repertoire of potential targets for new drugs against human diseases. But not all PPIs...

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Jun 10, 2021 Celine Tam 0 comments
Monopar Announces New Drug Candidate, MNPR-202, and Enters into Collaboration Agreement with the National University of Singapore for Preclinical Evaluation in Cancer

June 4, 2021

WILMETTE, Ill., June 03, 2021 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company primarily focused on...

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Jun 04, 2021 Celine Tam 0 comments
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