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Executive and Professionals – Cancer Science Institute of Singapore (CSI)

Software Engineer – GeDaC

BACKGROUND

The position of Software Engineer is immediately available in the Genome and Data Analytics Core (GeDaC) at the Cancer Science Institute of Singapore (CSI) — a part of National University of Singapore. The CSI GeDaC is building a platform to facilitate the automated processing and analysis of large cancer genomics datasets. Successful candidates, in conjunction with bioinformatics experts, will help provide interfaces (GUIs, APIs, etc.) to facilitate scalable data processing and analytics. This position provides a unique opportunity to help build a state-of-the-art, cloud-based platform to drive novel discoveries in cancer genomics and precision oncology.

RESPONSIBILITIES

Help develop and maintain frontend & API for our data analytics portal (deployed on AWS)
Work with the Bioinformatics Team to lay analytical tools over cancer genomics data
Work with DevOps Engineer to:
- Build cost-effective analytics via AWS microservices and serverless architecture (Lambda, Fargate, Aurora, etc.)
- Establish CI/CD pipelines for critical GeDaC software
Act as software czar to ensure best coding practices throughout GeDaC (Git, containerization, etc.)

REQUIREMENTS

Bachelors or Masters degree (minimally) in computer science, information systems, bioinformatics, engineering, mathematics, or related fields
2+ years of software engineering experience
Experience with interface design, development, and implementation
Strong Python and/or JavaScript programming skills
Proficient with collaborative software development via GitHub/GitLab
Excellent written and spoken English

PREFERENCES

Some knowledge of biology and geneticsInterest in statistics and data science
Demonstrable software development skills via GitHub/GitLab
Experience building using the AWS software stack
AWS certifications

HOW TO APPLY

Applications should include full curriculum vitae, github/gitlab handle, and contact information for 2-3 referees. Please also include a single page cover letter summarizing your experience, programmatic expertise, and why this position is of interest to you.

Dr. Jason J. Pitt
Special Fellow
Email: jason.j.pitt[at]nus.edu.sg

DevOps Software Engineer – GeDaC

BACKGROUND

The position of DevOps Software Engineer is immediately available in the Genome and Data Analytics Core (GeDaC) at the Cancer Science Institute of Singapore (CSI) — a part of National University of Singapore. The CSI GeDaC is building a platform to facilitate the automated processing and analysis of large cancer genomics datasets. Successful candidates, in conjunction with bioinformatics experts, will build and optimize various components of this platform. This position provides a unique opportunity to apply DevOps skills to Amazon Web Services (AWS), data-intensive computing, and artificial intelligence to drive novel discoveries in cancer genomics.

RESPONSIBILITIES

Participate in the continued development of:

Deploy and optimize of scalable genome processing workflows on AWS
Facilitate cost-effective analytics via AWS microservices and serverless architecture (Lambda, Fargate, Aurora, etc.)
Assist with database design, implementation, and management
Enable unit testing and deployment automation (CI/CD)
Help manage data ingress and egress to S3/Glacier

REQUIREMENTS

Bachelors or Masters degree (minimally) in computer science, information systems, bioinformatics, engineering, mathematics, or related fields
2+ years of DevOps experience
Strong Python programming skills and proficiency with Unix-based systems
Experience with collaborative software development via github/gitlab
Database management experience (SQL, NoSQL, Elasticsearch, etc.)
Excellent written and spoken English

PREFERENCES

Some knowledge of biology and genetics
Software development experience in industry
Past projects using CI/CD tools on commercial clouds
Experience with on-prem to cloud data migrations
AWS certifications

HOW TO APPLY

Dr. Jason J. Pitt
Special Fellow
Email: jason.j.pitt[at]nus.edu.sg

Scientific Officer

To provide administrative support to the CSI and its Principal Investigators on grant related matters.

Duties & Responsibilities

Assist with grant applications, manage the review process, and provide administrative support for the IRB, IACUC, safety/risk and other research regulatory requirements
Provide primary support and assistance on regular progress/ appraisal/other reports as required under grant terms and conditions
Preparation of budgets for research grants, virements and tracking of grants
Collation and updating biosketches of PI for collaborative grants and reporting for other purposes, for eg chaired professorship and annual appraisals
Liaise with NUS & NUHS research offices, Office of Legal Affairs and ILO (on issues of intellectual property, project and research collaboration agreements, MTAs, NDAs, etc.) and external funding agencies
Assist with preparation and submission of requests for external funding, including grants, research collaboration agreements, project agreements, sub-awards, and contracts
Assist to organise visits of review panels or advisory boards when required under senior management direction and according to grants’ terms and conditions
Manage administration issues in conjunction with the NUS research offices, Office of Financial Services and CSI Grants and Finance Teams.
Ensure good and tidy document housekeeping and timely correspondence:
- Maintain letters of award, approvals, amendments, etc.
- Maintain computerized financial data and progress reports
Assure that policies and procedures for compliance with research-related regulations are up-to-date and reviewed regularly
Assist in scheduling appointments, writing meeting minutes and coordinating research/other meetings as well as following up decisions made and other necessary actions as required
Compile bibliometrics and additional information for presentation slides, writeup and design of CSI Annual Report as well as other reports as required
Work with Outreach Team, NUS and NUHS corporate communications teams and coordinate with scientists on press releases when needed
Any other duties as may be assigned by senior management

Requirements:

Degree in Life Sciences, Medicine, or related field
Preference will be given to candidates with experience in coordinating and tracking multiple projects and their progress towards grant requirements
3 to 4 years’ experience in a similar position or laboratory supervisory position
Good team player
Excellent writing and reporting ability
Excellent communication and presentation skills

Applications should include full curriculum vitae and indicate the names of at least 2 referees.

Please send applications to:

Cancer Science Institute of Singapore
National University of Singapore Centre for Translational Medicine,
14 Medical Drive, #12-01,
Singapore 117599
Email: csi_recruitment@nus.edu.sg
Website: www.csi.nus.edu.sg

Please note that only shortlisted candidates will be contacted.

Laboratory Executive – Prof Chng Wee Joo’s lab

To provide support to the Principal Investigator and his team in terms of research, laboratory and administrative needs.

Duties & Responsibilities
a) Research:

To carry out assigned experiments
To organise, preserve and present the results of the experiments in a logical manner
To properly and systematically record all experiments that have been assigned and their results
To analyse and plan further experiments under guidance
To assist in supervising, training and guiding attachment/undergraduate students where required

b) Laboratory:

To plan and ensure the needs and requirements of the team in terms of consumables
To ensure that the lab is adequately stocked with clean glassware, minor equipment, chemicals, etc. required for experiments
Responsible for the cleanliness and maintenance of equipment through regular checks
Required to assemble reagents, chemicals and media that are needed for experiments
To ensure that standard operating procedures and safety regulations are followed
Responsible for the general cleanliness of the lab

c) Administrative duties:

To plan and ensure that the overall lab administrative needs of the team are met
To assist the Principal Investigator in tracking his/her grants and other sources of funding
Responsible for purchasing necessary equipment, chemicals, reagents as required by the lab or project
Maintain a systematic and proper record of all purchases
Liaising between the vendors and the administrative office to ensure proper purchase requisitions, goods delivery and prompt payment of supplies

d) Any other duties as required

Requirements:

Background in genomics, molecular biology and flow cytometry is preferred
Committed, hardworkinq and motivated candidates with BSc or diploma are welcome to apply
Knowledge of:
- Basic principles and practices in the fields of biology, physiology and/or chemistry
- Quality assurance procedures applicable to a laboratory
- Principles, techniques and terminology used in the examination of clinical and animal samples
- Principles, techniques and terminology used in cancer biology
- Laboratory scientific resource material; laboratory equipment and its care
- Methods of scientific research and relevant scientific theories
- Government guidelines and regulations pertinent to laboratory safety and security
- Packaging and shipping of diagnostic, infectious and hazardous materials
- Appropriate computer operations, software and peripherals
- General rules for safe exposure and handling of chemical and biological hazards
- IRB, OSHE & IACUC regulations
Ability to:
- Perform laboratory tests

Applications should include full curriculum vitae and indicate the names of at least 2 referees.

Please send applications to:

Please note that only shortlisted candidates will be contacted.

Laboratory Executive – Assoc Prof Takaomi Sanda’s lab

A fulltime Laboratory Executive position will be available after January 2021.

Job Scope:
a) Research tasks: 40%

To maintain zebrafish colonies including breeding and genotyping.
To create transgenic and knockout zebrafish models, and perform xenograft studies.
To perform tumor monitoring study and mutagenesis screening.
To isolate tissues from the animals and analyze by flowcytometry.
To harvest cells, protein, RNA or DNA from animal tissues, cell lines or bacteria.
To perform experiments including PCR, immunoprecipitation and Western blot.

b) Administrative tasks: 30%

To maintain a systematic and proper record of animals, including annual reports.
To liaise with the core facilities, committees and the administrative office to assist research.
To be responsible for purchasing necessary chemicals, reagents and equipment as required by the lab or project.
To liaise with the vendors to ensure proper purchase requisitions, goods delivery and prompt payment of supplies.

c) Laboratory safety: 30%

To serve as a safety lead in the laboratory.
To create and review standard operating procedures and risk assessments.
Responsible for the general cleanliness of the lab and core facility.
To assemble reagents, chemicals and media that are needed for experiments.

Requirements:

University degree (biology, biomedical science, biotechnology or related area).
Ability to speak and write well in English.
Prior experience working with zebrafish model is necessary.
Knowledge of: 1) basic principles and practices in the fields of biology, 2) principles, techniques and terminology used in biology, 3) principles, techniques and terminology used in animal studies.
Appropriate computer operations, software and peripherals, including Microsoft Word, Excel and Powerpoint.

Applications should include full curriculum vitae and indicate the names of at least 2 referees.

Please send applications to:

Please note that only shortlisted candidates will be contacted.

Laboratory Executive – Prof Chng Wee Joo’s Lab

The laboratory executive will provide support to the Principal Investigator and her team in terms of research, laboratory and administrative needs.

Duties and Responsibilities:

a) Research:

To carry out assigned experiments
To conduct troubleshooting and refining of experimental procedures
To organise, preserve and present the results of the experiments in a logical manner
To properly and systematically record all experiments that have been assigned and their results
To analyse and plan further experiments under guidance
To keep abreast with the current research scene and to propose relevant techniques and latest technologies to answer hypothetical research questions
To assist in supervising, training and guiding attachment/undergraduate students where required

b) Laboratory:

To plan and ensure the needs and requirements of the team in terms of consumables
To ensure that the lab is adequately stocked with clean glassware, minor equipment, chemicals, etc. required for experiments
Responsible for the cleanliness and maintenance of equipment through regular checks
Required to assemble reagents, chemicals and media that are needed for experiments
To ensure that standard operating procedures and safety regulations are followed
Responsible for the general cleanliness of the lab

c) Administrative duties:

To plan and ensure that the overall research/lab administrative needs of the team are met, such as producing reports and preparing presentation slides
Responsible for purchasing necessary equipment, chemicals, reagents as required by the lab or project
Maintain a systematic and proper record of all purchases
Liaising between the vendors and the administrative office to ensure proper purchase requisitions, goods delivery and prompt payment of supplies

d) Any other duties as required

Requirements:

Background in genomics, cell and molecular biology, NGS and flow cytometry.
Committed, dedicated, diligent and motivated candidates with BSc or diploma are welcome to apply.
Willing to clock in extra hours (including coming back to the lab during the weekends) when there is an urgency to fulfill research deadlines
Willing to perform mouse work
A team player

Knowledge of:

Basic principles and practices in the fields of biology, physiology and/or chemistry
Principles, techniques and terminologies used in cancer biology
Scientific and cancer research methodologies
Principles, techniques and terminology used in the examination of clinical and animal samples
Scientific data analysis softwares such as FlowJo, CompuSyn and PRISM
Quality assurance procedures applicable to a laboratory
Government guidelines and regulations pertinent to laboratory safety and security
Packaging and shipping of diagnostic, infectious and hazardous materials
General rules for safe exposure and handling of chemical and biological hazards
IRB, OSHE & IACUC regulations

Applications should include full curriculum vitae and the names, addresses and contact numbers of 3 professional references. Please send applications to:

Laboratory Executive

To provide support to the Principal Investigator and his team in terms of research, laboratory and administrative needs.

Responsibilities

a) Research:

to carry out assigned experiments
to organise, preserve and present the results of the experiments in a logical manner
to properly and systematically record all experiments that have been assigned and their results
to analyse and plan further experiments under guidance
to assist in supervising, training and guiding attachment/undergraduate students where required

b) Laboratory:

to plan and ensure the needs and requirements of the team in terms of consumables
to ensure that the lab is adequately stocked with clean glassware, minor equipment chemicals, etc. required for experiments
responsible for the cleanliness and maintenance of equipment through regular checks
required to assemble reagents, chemicals and media that are needed for experiments
to ensure that standard operating procedures and safety regulations are followed
responsible for the general cleanliness of the lab

c) Administrative duties:

to plan and ensure that the overall lab administrative needs of the team are met
to assist the Principal Investigator in tracking his/her grants and other sources of funding
responsible for purchasing necessary equipment, chemicals, reagents as required by the lab or project
maintain a systematic and proper record of all purchases
liaising between the vendors and the administrative office to ensure proper purchase requisitions, goods delivery and prompt payment of supplies

d) Any other duties as required

Requirements

Degree in Life Sciences or its equivalent. Fresh graduates are welcome to apply.
Knowledge of mouse work is an added advantage
Ability to speak and write well in English

Knowledge of

Basic principles and practices in the fields of biology, physiology and/or chemistry.
Quality assurance procedures applicable to a laboratory.
Principles, techniques and terminology used in the examination of clinical and animal samples.
Principles, techniques and terminology used in cancer biology.
Laboratory scientific resource material; laboratory equipment and its care.
Methods of scientific research and relevant scientific theories.
Government guidelines and regulations pertinent to laboratory safety and security.
Packaging and shipping of diagnostic, infectious and hazardous materials.
Appropriate computer operations, software and peripherals.
General rules for safe exposure and handling of chemical and biological hazards
IRB, OSHE & IACUC regulations
Ability to:
- Perform laboratory tests
- Work cooperatively and effectively with others

Applications should include full curriculum vitae and the names, addresses and contact numbers of 3 professional references. Please send applications to:

Executive and Professionals

Software Engineer – GeDaC

DevOps Software Engineer – GeDaC

Scientific Officer

Laboratory Executive – Prof Chng Wee Joo’s lab

Laboratory Executive – Assoc Prof Takaomi Sanda’s lab

Laboratory Executive – Prof Chng Wee Joo’s Lab

Laboratory Executive

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