Research Positions Available
Several full-time postdoctoral positions are immediately available for MD and/or Ph.D graduates. Please state the name of the lab that you are applying to in the email subject.
Research Positions Available
Several full-time postdoctoral positions are immediately available for MD and/or Ph.D graduates. Please state the name of the lab that you are applying to in the email subject.
Are you a biomedical researcher motivated to pursue an outstanding career in cancer research with a focus on organoid research?
Cancer will affect more than 1 in 3 Singaporeans. At the Cancer Science Institute (CSI), our mission is to be at the global forefront of research to overcome this scourge. Our innovative international faculty, cutting-edge facilities, supportive working environment and competitive package together enable each of our staff to realize their maximum potential.
We now seek a Research Assistant/ Associate to join the team of Prof. Ashok Venkitaraman. This is an exciting opportunity to work closely with a world-leading cancer researcher to undertake pioneering research on the role of genome instability in human carcinogenesis (eg., see Venkitaraman Science (2014) PMID:24675954 and Venkitaraman DNA Repair (2019) PMID:31337537).
The role will provide expertise in the establishment, genetic manipulation and maintenance of human and murine cell cultures, performance of animal work as well as design/ perform and analyse work within the project parameters.
Duties & Responsibilities
Research:
o design, perform and analyse work with mouse models
o to carry out assigned molecular and cell biology experiments (i.e. cloning, FACS, western blotting, RNA, sequencing, microscopy) and perform analysis and determinations as tasked
o to organise, preserve and present the results of the experiments in a logical manner
o to properly and systematically record all experiments that have been assigned and their results
Lab Management:
o maintain up to date records of inventories for chemical/ biological reagents
o assist when required with procurement
o ensure tidiness and cleanliness of the lab is maintained
Requirements
Knowledge of:
o Basic principles and practices in the fields of biology.
o Principles, techniques and terminology used in cancer biology.
o Methods of scientific research and relevant scientific theories.
o Appropriate computer operations, software and peripherals.
o General rules for safe exposure and handling of chemical and biological hazards
o IRB, HBRA & IACUC regulations
o Principles, techniques and terminology used in organoid model systems and genomic and RNA sequencing as well as common lab molecular and cell biology techniques (desirable)
Ability to:
o Perform laboratory tests in an efficient and timely manner
o Work cooperatively and effectively with others
Apply here.
A research associate position is available immediately in Prof Daniel Tenen’s lab for a highly motivated Master or Ph.D. graduate with background in molecular or cellular biology, and bioinformatics to develop a novel, fully automated analysis pipeline for the newly emerging ChIP sequencing methods: “Cut and Run” and “Cut and Tag” in cancer related study. The successful candidate will help to design pipeline, conduct experiments pipelines, analyse data and write papers.
Qualifications:
Applications should include full curriculum vitae, publication list, and names and contact information of 3 referees. Please also include a summary of your research experience.
Apply here.
A postdoctoral position is available immediately for an extremely motivated Ph.D with a strong background in molecular or cellular biology, biochemistry, or other related fields. The successful candidate will help design and conduct experiments, analyse data, write papers and grants. Projects involve studying the novel mechanisms of replication stress and genome instability in cancers. An overview of research can be found at https://www.csi.nus.edu.sg/web/sriram/
Duties & Responsibilities
Requirements
Applications should include inside a single pdf document a CV, a summary of past research experience, a description of long term plans and names/contact information (including email) of 3 referees. Applications will be processed in a rolling basis. This position will remain open until filled or withdrawn.
Apply here.
A fulltime Laboratory Executive or Research Assistant position in the Fluorescence Activated Cell Sorting (FACS) Facility is available immediately. The successful candidate will aid the institute in providing flow cytometry service for users. The candidate can also choose to work on either research or administrative tasks under the supervision of A/Prof. Takaomi Sanda.
Requirements:
Job scope:
1. Fluorescence Activated Cell Sorting (FACS) Facility
2. *Research or Administrative Tasks
* The candidate can select either research track (appointed as a Research Assistant) or administrative tack (appointed as a Laboratory Executive).
2.a) Research tasks
b) Administrative tasks
Applications should include full curriculum vitae and indicate the names of at least 2 referees
Apply here.
A postdoctoral position is available immediately for an extremely motivated Ph.D. or M.D with a strong background in molecular or cellular biology, biochemistry, or other related fields. The successful candidate will help to design and conduct experiments, analyse data, write papers and grants, including fellowships, and mentor and direct PhD students. Projects involve RNA biology with relevance to cancer, the oncofetal protein SALL4 in cancer, or both; a list of publications can be found at http://www.ncbi.nlm.nih.gov/pubmed/?term=Tenen+DG
Qualifications:
Applications should include an NIH style biosketch, and names and contact information (including telephone numbers) of 3 referees. Request that letters of recommendation be sent to daniel.tenen@nus.edu.sg (informal email recommendations are fine). Include a summary of your past research experience, a description of your long term plans, as well as ideas for at least two projects that you might want to work on in Dr. Tenen’s lab (half page each is fine, have fun with this!).
Job Description
To provide support to the Principal Investigator in research projects, maintenance of laboratory inventory and administration. Research duties and responsibilities will include:
Key Responsibilities
Qualifications
Honors degree (2nd upper class and above) in Life Sciences or similar field.
Candidates with 3-4 years of experience in a cancer biology laboratory and/or postgraduates will have an advantage.
Job Requirements
Apply here.
A position is available immediately for an extremely motivated Ph.D., M.D., or M.D./Ph.D. with a strong background in bioinformatics. The successful candidate will help to design experiments, analyse data, write papers and grants, including fellowships, and mentor and direct PhD students. Projects involve RNA biology with relevance to cancer, the oncofetal protein SALL4 in cancer, or both; a list of publications can be found at http://www.ncbi.nlm.nih.gov/pubmed/?term=Tenen+DG
Qualifications:
Applications should include curriculum vitae, publication list, and names and contact information (including telephone numbers) of 3 referees. Request that letters of recommendation be sent to daniel.tenen@nus.edu.sg (informal email recommendations are fine). Include a summary of your past research experience, a description of your long term plans, as well as ideas for at least two projects that you might want to work on in Dr. Tenen’s lab (half page each is fine, have fun with this!).
Please note that only shortlisted candidates will be contacted.
Apply here.
Duties & Responsibilities
a) Research:
– to carry out assigned experiments
– to organise, preserve and present the results of the experiments in a logical manner
– to properly and systematically record all experiments that have been assigned and their results
– to analyse and plan further experiments under guidance
– to assist in supervising, training and guiding attachment/undergraduate students where required
b) Laboratory:
– to plan and ensure the needs and requirements of the team in terms of consumables
– to ensure that the lab is adequately stocked with clean glassware, minor equipment, chemicals, etc. required for experiments
– responsible for the cleanliness and maintenance of equipment through regular checks
– required to assemble reagents, chemicals and media that are needed for experiments
– to ensure that standard operating procedures and safety regulations are followed
– responsible for the general cleanliness of the lab
c) Administrative duties:
– to plan and ensure that the overall lab administrative needs of the PDO team are met
– to assist the Principal Investigator in tracking his/her grants and other sources of funding
– responsible for purchasing necessary equipment, chemicals, reagents as required for PDO research
– maintain a systematic and proper record of all purchases
– liaising between the vendors and the administrative office to ensure proper purchase requisitions, goods delivery and prompt payment of supplies
d) Any other duties as required
Qualifications
Apply here.
A research associate position is available immediately in Prof Daniel Tenen’s lab for a highly motivated Master or Ph.D. graduate with a background in molecular or cellular biology, biochemistry or other related fields who is interested in deciphering the functional roles of RNA editing enzymes in acute myeloid leukemia (AML). The successful candidate will help to design experiments, conduct experiments, analyse data, write papers and mentor students.
Qualifications:
Applications should include full curriculum vitae, publication list, and names and contact information of 3 referees. Please also include a summary of your research experience.
Please apply here.
Job Description
To provide support to the Principal Investigator in research projects, maintenance of laboratory inventory and administration. Research duties and responsibilities will include:
Qualifications
Honors degree (2nd upper class and above) in Life Sciences or similar field.
Candidates with 3-4 years of experience in a cancer biology laboratory and/or postgraduates will have an advantage.
Apply here.
Job Description
RESEARCH ASSISTANT
(Telomere Biology)
We are seeking a highly-motivated candidate for a research asssistant position available in the Kappei Lab at the Cancer Science Institute of Singapore. Our young and international team addresses research questions on nucleic acid-protein interactions with quantitative mass spectrometry, cell biological and genetic approaches applied to cancer research. Specifically, the successful candidate will be actively involved in a research project investigating how telomere-binding proteins mechanistically impact telomere homeostasis in cancer. This project will span a variety of experimental approaches, e.g. gene editing of cancer cell lines, expression analysis of mRNA and protein, mouse genetics as well as various mass spectrometry-based approaches to study DNA-protein and protein-protein interactions. Overall, the research assistant will support the research team in terms of research as well as laboratory and administrative needs.
Qualifications
Requirements:
• Degree in life sciences or equivalent; fresh graduates are welcome to apply
• Excellent communication skills and good team spirit
• Fluent in spoken and written English
• Outstanding organizational skills
Practical experience with proteomics research, molecular biology techniques and mouse handling are an added advantage but not a requirement.
Applications should include in a single PDF a 1-page cover letter, curriculum vitae, certificates of qualifications and the names and contact information of at least 2 professional references. Please send applications with the reference “Research Assistant DK Lab” to:
Dr. Dennis Kappei
Principal Investigator
CSI Singapore
Email: dennis.kappei[at]nus.edu.sg
Further information on the Cancer Science Institute of Singapore as well as working at CSI can be found on our website: www.csi.nus.edu.sg/web/careers/
Apply here.
Job Description
– Perform experiments involving mouse experiments, bench work and tissue culture.
– Analyze experiment data and interpret results properly.
– Present research findings at lab meetings and seminars.
– Contribute to collaborative projects.
– Assist in lab management.
Qualifications
Requirements:
– Applicants should possess a PhD or MD in cancer biology, life sciences, biomedical sciences, biochemistry, or equivalent from a well-recognized university.
– Experience in immunology and molecular and cell biology.
– High-level experience in hands-on use of a wide range of relevant research methods, including mouse model (xenograft, tail vein injection, etc.), CRISPR screening and other basic molecular and cellular biology techniques such as cell culture, cloning, real-time PCR, western blotting, immunoprecipitation, etc.
– Strong track record of research achievement evidenced by high-quality publications.
Application:
If you are interested to pursue a career with us, please write to patdl@nus.edu.sg with your CV. Only shortlisted candidates will be notified.
Apply here.
A Bioinformatics Postdoctoral Fellow (PDF) position is available immediately at the Cancer Science Institute (a part of The National University of Singapore) in the laboratory of Dr. Sriram Sridharan. The research will focus in the broad area of replication stress, DNA damage and genome integrity.
This is an exciting opportunity to deploy expertise in computational biology in an active multidisciplinary environment. The PDF will develop novel bioinformatics pipeline(s) to analyze and integrate unpublished/publicly available genomic(s) datasets. The objective is to establish new biomarkers as well as to generate experimentally testable hypotheses. The generated biomarkers and hypotheses will be tested in clinical/experimental datasets in collaboration with wet-lab scientists.
• Bioinformatics
o Utilize and/or develop novel computational algorithms and tools
o Aggregation and analysis of unpublished/publicly available datasets
o Investigate findings in experimental/clinical datasets
• Basic requirements
o PhD in genomics, bioinformatics, computer science, engineering or related fields
o Experience analysing data derived from high-throughput technologies
o Strong Python, bash and/or R programming skills
o Proficient with standard statistical analyses
o Experience with Unix-based systems
o Motivation to learn new and relevant biology
o Strong analytical and critical thinking skills
o Excellent written and spoken English
• Preferred qualifications
o Experience using HPC systems
For full consideration, please submit the following to Dr. Sriram Sridharan via email at srirvs@nus.edu.sg
o a single page cover letter summarizing your experience, programmatic expertise, and why this position is of interest to you
o full curriculum vitae, including list of publications and
o contact information for 3 referees
The position will remain open until filled or withdrawn.
Apply here.
The position of DevOps Software Engineer is immediately available in the Genome and Data Analytics Core (GeDaC) at the Cancer Science Institute of Singapore (CSI) — a part of National University of Singapore. The CSI GeDaC is building a platform to facilitate the automated processing and analysis of large cancer genomics datasets. Successful candidates, in conjunction with bioinformatics experts, will build and optimize various components of this platform. This position provides a unique opportunity to apply DevOps skills to Amazon Web Services (AWS), data-intensive computing, and artificial intelligence to drive novel discoveries in cancer genomics.
Duties And Responsibilities
Participate in the continued development of:
Qualifications
Preferences
Apply here.
Are you a biomedical researcher motivated to pursue an outstanding career in cancer research with a focus on organoid research?
Cancer will affect more than 1 in 3 Singaporeans. At the Cancer Science Institute (CSI), our mission is to be at the global forefront of research to overcome this scourge. Our innovative international faculty, cutting-edge facilities, supportive working environment and competitive package together enable each of our staff to realize their maximum potential.
We now seek a Research Assistant/ Associate to join the team of Prof. Ashok Venkitaraman. This is an exciting opportunity to work closely with a world-leading cancer researcher to undertake pioneering research on the role of genome instability in human carcinogenesis (eg., see Venkitaraman Science (2014) PMID:24675954 and Venkitaraman DNA Repair (2019) PMID:31337537).
The role will provide expertise in the establishment, genetic manipulation and maintenance of human and murine organoid cultures as well as design/ perform and analyse work within the project parameters.
Duties and Responsibilities
Research:
Lab Management:
Qualifications
Apply here.
Duties and Responsibilities
a) Research:
b) Laboratory:
c) Administrative duties:
d) Any other duties as required
Qualifications
Apply here.
We are seeking an enthusiastic and highly motivated Research Associate to aid in cell line development and maintenance at the NUS Centre for Cancer Research (N2CR) under the Tissue Specific Carcinogenesis (TSC) Theme.
Duties and Responsibilities
Qualifications
Apply here.
The Cancer Science Institute of Singapore (CSI) Career Accelerator Postdoctoral Fellowship invites outstanding applicants at the level of early-stage postdoctoral fellows. The awardees will be hosted within established research labs to develop their independent research programs and collaborate with other exceptional researchers. They will receive a competitive salary package with an annual research grant of up to SGD$25,000 per year and equipment grant of SGD$5,000. Access to state-of-the-art core facilities will be provided. The tenure is up to three years.
Applicants should fulfil the following criteria:
Interested applicants should submit the following to csi_recruitment@nus.edu.sg or attach the following documents in your application. Please indicate “Application for CSI Career Accelerator Postdoctoral Fellowship” in the subject title. Only shortlisted candidates will be contacted.
Apply via: https://career44.sapsf.com/sfcareer/jobreqcareer?jobId=6350&company=nationalunP2
Are you a biomedical researcher motivated to pursue an outstanding career in cancer research with a focus on organoid research?
Cancer will affect more than 1 in 3 Singaporeans. At the Cancer Science Institute (CSI), our mission is to be at the global forefront of research to overcome this scourge. Our innovative international faculty, cutting-edge facilities, supportive working environment and competitive package together enable each of our staff to realize their maximum potential.
We now seek a Research Scientist/ Fellow to join the team of Prof. Ashok Venkitaraman. This is an exciting opportunity to work closely with a world-leading cancer researcher to undertake pioneering research on the role of genome instability in human carcinogenesis (eg., see Venkitaraman Science (2014) PMID:24675954 and Venkitaraman DNA Repair (2019) PMID:31337537). The role will provide expertise in the establishment, genetic manipulation and maintenance of human and murine organoid cultures as well as design/ perform and analyse work within the project parameters.
Duties and Responsibilities
Research:
Qualifications
ESSENTIAL qualifications include: (1) a PhD with 1-3 years’ relevant post-doctoral experience, (2) strong track record of research achievement evidenced by high-quality publications in a relevant field, (3) high-level experience in hands-on use of a wide range of relevant research methods with a focus on organoid work, (4) skills in working independently and creatively to solve experimental problems and (5) effective communication and presentation skills, with experience in communicating scientific work including scientific papers, presentations and reports.
Preference will be given to candidates with: (1) Familiarity with the development of phenotypic assays for genetic or chemical screening, involving the use of flow cytometry, high-throughput high-content microscopy, and/or advanced fluorescence microscopy; (2) Previous experience with genetically engineered murine models, or (3) Knowledge of IRB, HBRA & IACUC regulations.
Apply here.
Are you a biomedical researcher motivated to pursue an outstanding career in cancer research with a focus on structural biology?
Cancer will affect more than 1 in 3 Singaporeans. At the Cancer Science Institute (CSI), our mission is to be at the global forefront of research to overcome this scourge. Our innovative international faculty, cutting-edge facilities, supportive working environment and competitive package together enable each of our staff to realize their maximum potential.
We now seek a Research Scientist/ Senior Research Scientist to join the team of Prof. Ashok Venkitaraman. This is an exciting opportunity to work closely with a world-leading cancer researcher to undertake pioneering research on the role of genome instability in human carcinogenesis (eg., see Venkitaraman Science (2014) PMID:24675954 and Venkitaraman DNA Repair (2019) PMID:31337537).
This position will be jointly under Dr. Tan Yong Zi, who is an expert on single-particle cryogenic electron microscopy (cryo-EM) (see https://www.tyzlab.com/). His lab is a core member of the Centre for BioImaging Sciences’ (CBIS), and have access to high-end cryo-EM microscopes, including a Titan Krios with K3 direct detector and energy filter. The aim of this joint position is to use cryo-EM to help solve the structures of many exciting cancer complexes to help with potential drug development.
Duties and Responsibilities
The position exists to provide
Qualifications
Please apply here.
Are you a biomedical researcher motivated to pursue an outstanding career in cancer research with a focus on structural biology?
Cancer will affect more than 1 in 3 Singaporeans. At the Cancer Science Institute (CSI), our mission is to be at the global forefront of research to overcome this scourge. Our innovative international faculty, cutting-edge facilities, supportive working environment and competitive package together enable each of our staff to realize their maximum potential.
We now seek a Research Scientist/ Senior Research Scientist to join the team of Prof. Ashok Venkitaraman. This is an exciting opportunity to work closely with a world-leading cancer researcher to undertake pioneering research on the role of genome instability in human carcinogenesis (eg., see Venkitaraman Science (2014) PMID:24675954 and Venkitaraman DNA Repair (2019) PMID:31337537).
This position will be jointly under Dr. Tan Yong Zi, who is an expert on single-particle cryogenic electron microscopy (cryo-EM) (see https://www.tyzlab.com/). His lab is a core member of the Centre for BioImaging Sciences’ (CBIS), and have access to high-end cryo-EM microscopes, including a Titan Krios with K3 direct detector and energy filter. The aim of this joint position is to use cryo-EM to help solve the structures of many exciting cancer complexes to help with potential drug development.
Duties and Responsibilities
The position exists to provide
Qualifications
Please apply here.
A postdoctoral position is available immediately in A/Prof Polly Chen’s groups for a highly motivated PhD graduate with experience in Bioinformatics (computational genomics). The focus of A/P Polly Chen’s lab is on the transcriptome-wide identification of RNA changes (e.g., RNA editing, alterative splicing, altered protein-RNA interactions, etc) in tumors and functional investigation of these changes in cancer.
Duties and Responsibilities
Candidates should have strong background in bioinformatics, genomics/transcriptomics, computer science, statistics, or other related fields. Those who are interested in computational genomics and transcriptomics, particularly in analysis and integration of various genomics/transcriptomics data, are encouraged to apply. The successful candidate will analyze and integrate in-house NGS datasets (bulk and single-cell RNA-seq, spatial transcriptomics, DNA-seq, eCLIP-seq, MeDIP-seq, etc) and also utilize publicly available genomic/transriptomics/clinical data sets to identify novel biological biomarkers/patterns and regulatory mechanisms.
Candidates are required to have a strong quantitative and statistics background, as well as strong programming skills (e.g. Python, Perl, C, C++, Java, R, or other related programming knowledge), and excellent skills in handling genomic, transcriptomic and proteomic databases. Experience in analyzing RNA editing, alternative splicing, RNA binding sites using the bulk and single-cell RNA-seq, eCLIP-seq, spatial transcriptomic data is a plus.
Qualifications
Please apply here.
A postdoctoral/SRS position is available immediately in Prof Chng Wee Joo’s groups for a highly motivated PhD graduate with experience in Bioinformatics (computational genomics). The focus of the lab is on deciphering transcriptional and genomic abnormalities in the context of blood cancer, including epigenetic and superenhancer deregulation, using single cell sequencing amongst other genomics techniques.
Candidates should have backgrounds in bioinformatics, genomics, computer science, statistics, or other related fields. Those who are interested in computational genomics, particularly in analysis of single cell sequencing data, superenhancer and chromatic interaction data, and integration of various genomics data, are encouraged to apply. The successful candidate will analyse and integrate in-house genomic (RNA-seq, small RNA-seq, microarray etc) data sets and also utilize publicly available genomic/clinical data sets to identify novel biological patterns and regulatory mechanisms.
Candidates are required to have a strong quantitative and statistics background, as well as strong programming skills (e.g. Python, Perl, C, C++, Java, R or other related programming knowledge), and excellent skills in handling Linux clusters and genomic databases. Experience in analyzing single cell and/or long-read sequencing data is ideal but not required.
Applications should send full curriculum vitae (not more than 3 pages) and the names, addresses and contact numbers of 3 professional references.
Apply here.
ROLES AND RESPONSIBILITIES
REQUIREMENTS
PREFERENCES
Apply here.
We are seeking a highly motivated candidate as a research fellow in the Quantitative Proteomics Core in collaboration with the Kappei lab at the Cancer Science Institute of Singapore (CSI). Our team addresses research questions on nucleic acid-protein interactions with quantitative mass spectrometry, cell biological and genetic approaches applied to cancer research and we further support research activities at CSI as part of the Quantitative Proteomics Core with quantitative proteomics solutions to study protein expression, protein interactions as well as post-translational modifications.
Proteins are the functional agents in cells, yet the systematic global characterization of their expression and spatial distribution has largely remained limited to the analysis of RNA as a proxy. To close this gap, we have recently expanded the Quantitative Proteomics Core to Clinical Proteomics applications with dedicated instruments including a timsTOF fleX mass spectrometer that allows for dual LC-MS/MS and MALDI imaging analysis. The research fellow will develop innovative workflows for both untargeted and targeted spatial protein imaging applied to the analysis of cancer tissues. We are offering a position in a stimulating, diverse and international research environment as well as the opportunity to gain expertise in a highly demanded technology using state-of-the-art instruments.
Requirements:
Applications should include in a single PDF a 1-page cover letter, curriculum vitae and the names and contact information of at least 2 professional references. Please send applications with the reference “Clinical Proteomics RF” to:
Dr. Dennis Kappei
Principal Investigator
CSI Singapore
Email: dennis.kappei[at]nus.edu.sg
Further information on the Cancer Science Institute of Singapore as well as working at CSI can be found on our website: www.csi.nus.edu.sg/web/careers/
Please apply here.
ROLES AND RESPONSIBILITIES
REQUIREMENTS
PREFERENCES
Apply here.
The position of Postdoctoral Fellow (PDF) in computational cancer genomics is immediately available at The Cancer Science Institute of Singapore (The National University of Singapore). This PDF will lead a newly funded project in the laboratory of Dr. Jason Pitt that will explore how germline genetics and cell-of-origin contribute to genomic instability (GI) in cancer (see Pitt et al., 2018, Nat Comms; Pitt et al., 2018, Cancer Cell; Wang & Pitt et al., 2019, Int J Cancer). The acquisition of GI by malignant cells is critical to cancer development and progression. However, the magnitude and type of GI can vary widely across patients and cancer types. Delineating the underlying sources of GI will help identify novel therapeutic biomarkers (Pitt, Hoppe, & Jeyasekharan; PCT/SG2021/050105). The PDF will build upon our recently developed computational framework to derive dozens of GI scores and copy number signatures from tens of thousands of malignant samples. Using a multi-omic approach, these scores will be associated with clinical, genomic, and cell-type specific features. Candidate genes/variants will be investigated experimentally using CRISPR-mediated isogenic cell lines.
ROLES AND RESPONSIBILITIES
REQUIREMENTS
PREFERENCES
Apply here.
To provide support to the Principal Investigator in research projects, maintenance of laboratory inventory and administration. Research duties and responsibilities will include:
The Research Assistant is also required to cooperate in maintaining and planning for the needs of the lab team as well as to meet administrative duties that are assigned.
Honors degree (2nd upper class and above) in Life Sciences or similar field.
Candidates with 3-4 years of experience in a cancer biology laboratory and/or postgraduates will have an advantage.
Apply here.
The position of Postdoctoral Fellow (PDF) — with an emphasis on computational cancer genomics — is immediately available at The Cancer Science Institute of Singapore (a part of The National University of Singapore). The postholder will work with the laboratories of Prof. Ashok Venkitaraman, Dr. Jason Pitt and Prof. Touati Benoukraf on a project studying the evolution of cancer genomes during early steps in carcinogenesis, with the long-term aim to develop better methods for early intervention.
This is an exciting opportunity to deploy expertise in computational biology in an active multidisciplinary environment, working closely with experimental cancer biologists to address major scientific problems.
The postholder will apply existing analytic pipelines and devise new algorithms to explore data derived from multiple DNA sequencing technologies (eg., Illumina & Nanopore) to resolve cancer genome evolution at the clonal level. S/he will also analyse complementary data from other technologies, ranging from single-cell RNAseq to chromatin immunoprecipitation to chromatin accessibility (ATAC-seq), using a variety of novel cellular models established in Prof. Venkitaraman’s laboratory. Experimental findings will be explored and validated using clinical genomic datasets.
A PhD in a relevant field, with a strong track record of achievement exemplified by publications, is important, as is the required expertise in computational biology listed below. Experience in the methods to be used in the project is desirable.
Requirements:
Preferences:
Please click here to apply.
BACKGROUND
The position of Postdoctoral Fellow with an emphasis on cancer genomics and bioinformatics is immediately available in the laboratory of Dr. Jason Pitt, which integrates data science and biological expertise to facilitate precision oncology. The Pitt Laboratory achieves this by developing cutting-edge software that allows rapid interrogation and interpretation of large genomic datasets. This position is connected to the Cancer Science Institute (CSI) Translational theme, which is building knowledge-bases and algorithms to recommend cancer treatments based on a patient’s genetic profile. This fellow will also work closely with clinician-scientist Dr. Anand Jeyasekharan to help facilitate molecular tumor boards at National University Hospital. An experienced genome analyst will have the unique opportunity to impact real-world precision oncology while developing skills in cloud computing, data science, and augmented intelligence.
RESPONSIBILITIES
Candidate will work with the CSI Translational Team to deliver the following:
REQUIREMENTS
PREFERENCES
HOW TO APPLY
Applications should include full curriculum vitae, publication list (if applicable), and contact information for 2-3 referees. Please also include a single page cover letter summarizing your previous research, analytical/programmatic expertise, and why this position is of interest to you.
Apply via:
https://career44.sapsf.com/sfcareer/jobreqcareer?jobId=5336&company=nationalunP2
Dr. Jason J. Pitt
Special Fellow
Email: jason.j.pitt[at]nus.edu.sg
Are you a biomedical researcher motivated to pursue an outstanding career in cancer research?
Cancer will affect more than 1 in 3 Singaporeans. At the Cancer Science Institute (CSI), our mission is to be at the global forefront of research to overcome this scourge. Our innovative international faculty, cutting-edge facilities, supportive working environment and competitive package together enable each of our staff to realize their maximum potential.
We now seek a Senior Research Scientist to join the team of our new Director, Prof. Ashok Venkitaraman, who has recently joined us from the University of Cambridge (see https://www.csi.nus.edu.sg/web/ashok-venkitaraman/). This is an exciting opportunity to work closely with a world-leading cancer researcher to undertake pioneering research on the role of genome instability in human carcinogenesis (eg., see Venkitaraman Science (2014) PMID:24675954 and Venkitaraman DNA Repair (2019) PMID:31337537).
ESSENTIAL qualifications include: (1) a PhD with 3 years’ relevant post-doctoral experience, (2) strong track record of research achievement evidenced by high-quality publications in a relevant field, (3) high-level experience in hands-on use of a wide range of relevant research methods, (4) skills in working independently and creatively to solve experimental problems and (5) effective communication and presentation skills, with experience in communicating scientific work including scientific papers, presentations and reports.
Preference will be given to candidates with: (1) Previous experience in computational approaches to the analysis of (epi)genomic, transcriptomic or proteomic alterations in cancer or other diseases; (2) Familiarity with the development of phenotypic assays for genetic or chemical screening, involving the use of flow cytometry, high-throughput high-content microscopy, and/or advanced fluorescence microscopy, or (3) Previous experience with genetically engineered murine models.
More information on careers in NUS can be found at http://www.nus.edu.sg/careers/
Please submit applications including (1) a covering letter that explains why you are suited to this post, (2) a detailed CV, and (3) the contact details of 3 professional referees including your last position to:
Cancer Science Institute of Singapore
National University of Singapore Centre for Translational Medicine,
14 Medical Drive, #12-01,
Singapore 117599
Email: csi_recruitment@nus.edu.sg
Website: www.csi.nus.edu.sg
Applications will be considered until the position is filled.
We will only contact candidates who are shortlisted.
A fulltime Research Fellow position will be available after January 2021.
The primary focus of our laboratory is to understand the mechanism of transformation by aberrant activation of oncogenic transcription factors in leukemia and other cancers. We are seeking highly motivated graduates. Candidates should have a PhD degree in molecular biology, cancer biology, medicine, bioinformatics, computational biology, computer science, or related fields.
The ability to work independently and design and interpret experiments is essential, together with excellent organizational skills and fluency in English. We are looking for a team- and goal-oriented personality who wants to work in a young and international team. Research Fellow will be encouraged to present data at internal and external meetings and publish in peer-reviewed journals.
Applications should include full curriculum vitae, publication list, information on years of experience in research work, and names and contact information (e-mail and telephone numbers) of 3 references. Inclusion of a summary of your research experience and a brief paragraph on why you want to join the Sanda lab is highly suggested.
Please note that only shortlisted candidates will be contacted.
Please send applications to:
Cancer Science Institute of Singapore
National University of Singapore Centre for Translational Medicine,
14 Medical Drive, #12-01,
Singapore 117599
To apply for this position, please visit this link here.
Website: www.csi.nus.edu.sg
A postdoctoral position is available immediately in A/Prof Henry Yang and Dr Yvonne Tay’s groups for a highly motivated PhD graduate with experience in Bioinformatics (computational genomics). The focus of the lab is on deciphering regulatory RNA networks in the context of cancer (reviewed in Tay et al, Nature 2014; also see Tay et al, Cell 2011; Chan et al, NAR 2018).
Candidates should have backgrounds in bioinformatics, genomics, computer science, statistics, or other related fields. Those who are interested in computational genomics, particularly in analysis and integration of various genomics data, are encouraged to apply. The successful candidate will analyse and integrate in-house genomic (RNA-seq, small RNA-seq, microarray etc) data sets and also utilize publicly available genomic/clinical data sets to identify novel biological patterns and regulatory mechanisms. Candidates are required to have a strong quantitative and statistics background, as well as strong programming skills (e.g. Python, Perl, C, C++, Java, R or other related programming knowledge), and excellent skills in handling Linux clusters and genomic databases. Experience in analyzing single cell and/or long-read sequencing data is ideal but not required.
Applications should send full curriculum vitae (not more than 3 pages) and the names, addresses and contact numbers of 3 professional references to csiyangh@nus.edu.sg and yvonnetay@nus.edu.sg with the subject title – ‘Application for HY/YT postdoc position’.
Cancer Science Institute of Singapore
Centre for Translational Medicine
14 Medical Drive, #12-01,
Singapore 117599