H. Phillip KOEFFLER
Senior Principal Investigator, Cancer Science Institute of Singapore, National University of Singapore
Distinguished Visiting Professor, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore
Senior Consultant, Department of Haematology-Oncology, National University Hospital
Professor of Medicine, Cedars-Sinai Medical Center/UCLA
The major focus of Prof Koeffler’s lab is identifying key DNA abnormalities in cancers and translating these findings into novel classifications and diagnoses. In addition, his team has begun looking for new therapeutic approaches based on the DNA changes that occur in these tumours. They have learned that not only do tumours have common unifying DNA changes, each have unique DNA changes. Therefore successful therapy will require the ability to survey rapidly the entire genome for alterations so that they can tailor therapy.