The White lab studies the coordinated action of networks of genes that control developmental, disease and evolutionary processes. We have particular focus on discovery of genetic factors that contribute to cancer development and progression, and on building genome-wide models of transcriptional networks.
The White lab studies the coordinated action of networks of genes that control developmental, disease and evolutionary processes. We have particular focus on discovery of genetic factors that contribute to cancer development and progression, and on building genome-wide models of transcriptional networks. We use an integrated approach that makes use of genome and transcriptome sequencing, large-scale protein-protein and protein-DNA interaction analyses, measurement of chromatin state, systematic RNAi and CRISPR mutational analysis, and high throughput functional analyses of genomic regulatory elements. We are also particularly interested in the transcriptional networks controlled by nuclear receptor proteins in development and disease. We also have recently built novel algorithms for discovering tumor drivers and tumor risk factors from large-scale sequencing data, such as those available from The Cancer Genome Atlas.
Principal Associate, Cancer Science Institute of Singapore, National University of Singapore
B. James and Karen Frank Family Professor of Human Genetics, Ecology and Evolution, and Medicine; Director, Institute for Genomics and Systems Biology The University of Chicago
| Year(s) | Degree (if applicable) | Institute |
| 1998 | Ph.D. Developmental Biology | Stanford University |
| 1993 | B.Sc., M.Sc. Biology | Yale University |
| 2006 – Present | Director, Institute for Genomics and Systems Biology, The University of Chicago |
| 2006 – Present | Professor, The University of Chicago Dept. Human Genetics |
| 2004 – 2006 | Assoc. Prof., Yale University Dept. Genetics |
| 2001 – 2004 | Assist. Prof., Yale University Dept. Genetics |
| 1998 – 2000 | Postdoctoral Fellow, Stanford Genome Technology Center and Dept. Biochemsitry |
| 2007 – 2009 | Pritzker Fellow, The University of Chicago Pritzker School of Medicine |
| 2006 – 2009 | Investigator, Searle Chicago Biomedical Consortium |
| 2008 | Crain’s Business 40 under 40 |
| 2004 – 2008 | Arnold and Mabel Beckman Young Investigator |
| 2003 – 2006 | W. M. Keck Distinguished Young Investigator in Biomedical Sciences |
| 2000 – 2005 | NIH/NHGRI Genome Scholar Award |
| 1998 – 2000 | Helen Hay Whitney Foundation Fellow, Genome Technology Center, Stanford University |
| 1993 – 1998 | HHMI Predoctoral Fellowship, Department of Developmental Biology, Stanford University |
| 1993 | B.S., M.S. awarded magna cum laude, Phi Beta Kappa, Belknap Award for Outstanding Graduating Senior in the Natural Sciences at Yale University |
Gene regulatory systems, cancer genomics and systems biology, computational biology, statistical genomics, precision oncology and medicine, ‘big data’ analytics and infrastructure.
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