Principal Investigator, Cancer Science Institute of Singapore, NUS
Assistant Professor, Department of Biochemistry, Yong Loo Lin School of Medicine, NUS
Cancer is recognized conventionally as a genetic disease, caused by changes in the sequence of DNA (mutations). However, recent research highlights the critical role played by epigenetic factors in regulating tumor formation and progression. Epigenetic changes are those which result in alteration of gene expression but are not reflected in the DNA sequence, instead influence how the cells read the information contained in the DNA. My group is interested in studying epigenetic changes and their role in tumorigenesis.