LNK (SH2B3): paradoxical effects in ovarian cancer (Oncogene, Apr 2014)

LNK (SH2B3) is an adaptor protein studied extensively in normal and malignant hematopoietic cells. In these cells, it downregulates activated tyrosine kinases at the cell surface resulting in an antiproliferative effect. To date, no studies have examined activities of LNK in solid tumors. In this study, we found by in silico analysis and staining tissue

2014 Avon Foundation-AACR International Travel Grant awarded to Dr Wang Tingting

Our heartiest congratulations to Dr Wang Tingting for receiving the 2014 Avon Foundation-AACR International Travel Grant. This award provides travel support to abstract presenters working in breast cancer or other female cancers travelling from countries where opportunities for scientific advancement are limited. Title: Simvastatin induced apoptosis and suppressed proliferation of breast cancer through deactivating PI3K/Akt/mTOR