The Warburg Effect and Drug Resistance (British Journal of Pharmacology, Dec 2015)

Bhaskar Bhattacharya1, Mohd Feroz Mohd Omar2 and Richie Soong1,2 1Cancer Science Institute of Singapore, National University of Singapore, Singapore 2Department of Pathology, National University of Singapore, Singapore Abstract: The Warburg effect describes the increased utilization of glycolysis rather than oxidative phosphorylation by tumour cells for their energy requirements under physiological oxygen conditions. This effect has been

Acetylation of C/EBPα Inhibits its Granulopoietic Function (Nature Commun, Mar 2016)

Bararia D1,2,3,4,5,6, Kwok HS1,7, Welner RS8,9, Numata A1, Sárosi MB10, Yang H1, Wee S11, Tschuri S3,4,5,6, Ray D12, Weigert O3,4,5,6, Levantini E2,8,13, Ebralidze AK2,8, Gunaratne J11,14, Tenen DG1,2,8 1Cancer Science Institute, National University of Singapore, Singapore 117599, Singapore. 2Dana Farber/Harvard Cancer Center, Boston, Massachusetts 02215, USA. 3Department of Internal Medicine III, University Hospital of the

STEM Series Part 1: Igniting the Girls’ Passion in Science

The buzz is all about “Application”. People are driven not only by how much they know, but also in applying the knowledge to various aspects of life. It is important to nurture curious and analytical minds which can make sense of information and apply it to the world around us. These are the types of