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CSI Graduate Program Students’ Outing

The CSI Graduate Students Society organized an outing in October 2016 with the aims to foster closer ties among students, unwind from the hectic laboratory work and have fun. This year, the committee organized a two part event: a Trivial Pursuit Night, followed by a Resorts World Sentosa Halloween Horror Night. The Trivial Pursuit is a

EGFR kinase inhibitors and gastric acid suppressants in EGFR-mutant NSCLC: a retrospective database analysis of potential drug interaction. (Oncotarget, Nov 2016)

Kumarakulasinghe NB1 , Syn N1,2,3 , Soon YY4 , Asmat A5 , Zheng H6 , Loy EY6 , Pang B2,7 , Soo RA1,2. 1 Department of Haematology-Oncology, National University Cancer Institute, Singapore. 2 Cancer Science Institute of Singapore, National University of Singapore, Singapore. 3 Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 4 Department of Radiation Oncology, National University

Xenograft Cancer Models Facility

The Xenograft Cancer Models Facility, a research core facility in CSI Singapore established under the leadership of Dr Chan Shing Leng, maintains strains of immunocompromised mice for xenograft experiments. In this facility, the recently developed transplantable patient-derived cancer tissue xenograft (PDX) lines generated by grafting of fresh cancer tissues in immunodeficient mice (eg. NOD/SCID, NSG

Whole Genome DNA Methylation: Beyond Genes Silencing. (Oncotarget, Nov 2016)

Tirado-Magallanes R1,2, Rebbani K1, Lim R1, Pradhan S3, Benoukraf T1 1Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore, Singapore. 2Computational Systems Biology Team, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), INSERM, Ecole Normale Supérieure, PSL Research University, 75005 Paris, France. 3New England Biolab Inc., Ipswich, MA 01938, USA. Abstract The combination

Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia. (Cancer Res, Nov 2016)

Ding L1, Sun QY2, Tan KT2, Chien W3, Thippeswamy AM3, Eng Juh AY3, Kawamata N3, Nagata Y4, Xiao JF3, Loh XY2, Lin DC2, Garg M5, Lim SL3, Liu LZ2, Madan V5, Jiang YY2, Xu L6, Sanada M7, Fernández LT2, Preethi H2, Lill M8, Kantarjian H9, Kornblau SM10, Miyano S11, Ogawa S12, Liang DC13, Shih LY14,