Congratulations to our CSI PhD student Hong Huiqi from Dr Polly Chen’s lab! Huiqi’s abstract titled ‘DEAH Box Helicase 9 (DHX9) as a Bidirectional Regulator of Adenosine-to-Inosine (A-to-I) Editing’ was selected for presentation at the 5th Heidelberg Forum for Young Life Scientists. Along with the selection of her abstract, Huiqi was also awarded a travel
Combined use of irinotecan with histone deacetylase inhibitor belinostat could cause severe toxicity by inhibiting SN-38 glucuronidation via UGT1A1. (Oncotarget, Feb 2017)
Wang L1,2, Chan CE1,3, Wong AL1,4, Wong FC1, Lim SW3,4, Chinnathambi A5, Alharbi SA5, Lee LS2, Soo R1,4, Yong WP1,4, Lee SC1,4, Ho PC3, Sethi G2,5,6, Goh BC1,2,4. 1 Cancer Science Institute of Singapore, National University of Singapore, Singapore. 2 Department of Pharmacology, National University Health System, Singapore. 3 Department of Pharmacy, National University of
Individualised multiplexed circulating tumour DNA assays for monitoring of tumour presence in patients after colorectal cancer surgery. (Sci Rep, Jan 2017)
Ng SB1, Chua C2, Ng M2, Gan A3, Poon PS1, Teo M4, Fu C5, Leow WQ6, Lim KH6, Chung A7, Koo SL2, Choo SP2, Ho D2, Rozen S8, Tan P8,9, Wong M5, Burkholder WF1, Tan IB2,3,8. 1 Microfluidics Systems Biology, Institute of Molecular and Cell Biology, Singapore. 2 Division of Medical Oncology, National Cancer Centre
Clinical implications of DNMT3A mutations in a Southeast Asian cohort of acute myeloid leukaemia patients. (J Clin Pathol, Jan 2017)
Tan M1, Ng IK1, Chen Z2, Ban K2, Ng C3, Chiu L3, Seah E4, Lin M3, Tai BC5, Yan B3, Ng CH4, Chng WJ4,6,7. 1 Department of Biochemistry, National University of Singapore, Singapore, Singapore. 2 Investigational Medicine Unit, National University Health System, Singapore, Singapore. 3 Department of Laboratory Medicine, Molecular Diagnosis Centre, National University Health System, Singapore, Singapore.
Cai W1, Xiong Chen Z1, Rane G1, Satendra Singh S1, Choo Z1, Wang C1, Yuan Y1, Zea Tan T1, Arfuso F1, Yap CT1, Pongor LS1, Yang H1, Lee MB1, Cher Goh B1, Sethi G1, Benoukraf T1, Tergaonkar V1, Prem Kumar A2. Cancer Science Institute of Singapore, National University of Singapore, Singapore (WC, GR, SSS, CW,