Viewing

Frontiers in Cancer Science 2018

   The annual Frontiers in Cancer Science (FCS) conference marked its 10th Anniversary this year with the successful conclusion of its 10th meeting this year, held from 12-14 November at the University Cultural Centre, NUS. Proudly and jointly organized by the Cancer Science Institute of Singapore (CSI Singapore), Duke-NUS Medical School (Duke-NUS), Genome Institute of

MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles. (Nucleic Acids Res, Oct 2018)

Xuan Lin QX1, Sian S1, An O1, Thieffry D2, Jha S1,3, Benoukraf T1,4. Author information 1Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. 2Computational Systems Biology Team, Institut de Biologie de l'École Normale Supérieure (IBENS), INSERM, École Normale Supérieure, PSL Research University, Paris, France. 3Department of Biochemistry, National University of Singapore, Singapore, Singapore. 4Discipline of Genetics, Faculty of

Maftools: efficient and comprehensive analysis of somatic variants in cancer. (Genome Res, Nov 2018)

Mayakonda A1,2, Lin DC3, Assenov Y2,4, Plass C2,4, Koeffler HP1,3,5. Author information 1Cancer Science Institute of Singapore, National University of Singapore, 117599, Singapore. 2Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. 3Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA. 4German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany. 5National University Cancer Institute, National University Hospital,

[Review] Role of tumor-derived exosomes in cancer metastasis. (Biochim Biophys Acta Rev Cancer, Nov 2018)

Wee I1, Syn N1, Sethi G2, Goh BC3, Wang L4. Author information 1Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore. 2Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore. Electronic address: phcgs@nus.edu.sg. 3Cancer Science Institute of Singapore, National

Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation. (Cell Rep, Nov 2018)

Nakamura-Ishizu A1, Matsumura T2, Stumpf PS3, Umemoto T4, Takizawa H4, Takihara Y2, O'Neil A2, Majeed ABBA2, MacArthur BD5, Suda T6. Author information 1Cancer Science Institute, National University of Singapore, 14 Medical Drive, MD6, 117599 Singapore, Singapore; International Research Center for Medical Sciences, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto City 860-0811, Japan. Electronic address: ayaknakm@gmail.com. 2Cancer Science Institute, National University of Singapore, 14 Medical Drive,

Decoding transcriptomic intra-tumour heterogeneity to guide personalised medicine in ovarian cancer. (J Pathol, Oct 2018)

Tan TZ1, Heong V1,2,3, Ye J1, Lim D4,5, Low J6, Choolani M6, Scott C3, Tan DSP1,2,7, Huang RY1,6,8. Author information 1Cancer Science Institute of Singapore, National University of Singapore, Center for Translational Medicine, 14 Medical Drive,MD6 #12-01, Singapore 117599. 2Department of Haematology-Oncology, National University Cancer Institute Singapore, Level 8 NUH Medical Center, 5 Lower Kent Ridge Road, Singapore 119074. 3Walter and Eliza Hall Institute of Medical Research,

A novel SOCS5/miR-18/miR-25 axis promotes tumorigenesis in liver cancer. (Int J Cancer, Sep 2018)

Sanchez-Mejias A1, Kwon J1, Chew XH1, Siemens A1, Sohn HS1, Jing G1, Zhang B1, Yang H1, Tay Y1,2. Author information 1Cancer Science Institute of Singapore, Centre for Translational Medicine, National University of Singapore, Singapore 117599, Singapore. 2Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore. Abstract The role of miRNAs with tumor suppressive activity in liver cancer has been well