Research

Research Positions Available 

Several full-time postdoctoral positions are immediately available for MD and/or Ph.D graduates. Please state the name of the lab that you are applying to in the email subject.

Research Assistant - A/Prof Henry Yang

A full-time Research Assistant position is immediately available at the Bioinformatics Core, Cancer Science Institute of Singapore. The primary focus of our group is to analyze and integrate various genomic data for novel discoveries in cancer genomics. For this particular position, we are seeking highly motivated graduates who are interested in integration of human genomic data with microbiome data. The candidate will develop an integrative computational analysis platform for profiling interactions between human host and microbiome based on different genomics data.

Requirement:

Candidates should have a Bachelor’s degree in bioinformatics, computational biology or related fields. Knowledge and experience in genomics, genome sequence analysis, and transcriptome data analysis are required. Candidates should also have solid programming skills (e.g., Python, Perl, Java, R) as well as strong mathematical analytics background.

Applications should include full curriculum vitae and 2-3 reference letters. Please note that only shortlisted candidates will be contacted.

A/Prof Henry Yang
Head of Bioinformatics Core
Email: csiyangh[at]nus.edu.sg
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Research Assistant/Research Fellow (Bioinformatics) – Takaomi Sanda Lab

A full-time Research Fellow or Research Assistant position will be available after mid-August 2018. The primary focus of our laboratory is to understand the mechanism of transformation by aberrant activation of oncogenic transcription factors in acute leukemia through combining cancer genomics with functional genetics and bioinformatics. We also study non-coding RNAs and post-transcriptional mechanisms. Our long-term goal is to develop novel therapeutics targeting oncogenic pathways in cancer.

We are seeking highly motivated graduates. The candidate will analyze large scale genomic and transcriptomic data from next generation sequencing (whole genome sequencing, ChIP-seq, RNA-seq, Hi-C, 4C, etc), to study genomic abnormalities and transcriptional regulatory mechanisms in leukemia and normal hematopoietic cells. Candidates that are interested to work with leukemia biology are highly encouraged to apply.

Candidates should have a Bachelor’s degree (for Research Assistant position) or PhD degree (for Research Fellow position) in bioinformatics, biostatistics, computational biology, computer science or related fields. Knowledge for optimization and statistical packages and programming (e.g., Python, Perl, C, C++, Java, R, or other related programming knowledge) as well as the ability to work in a Linux environment are required. Research Fellow candidates should have experience in one or more of the following areas: 1) genome sequence analysis, 2) transcriptome analysis, 3) molecular modeling and simulation of biological systems.

The ability to work independently and design and interpret experiments is essential, together with excellent organizational skills and fluency in English. We are looking for a team- and goal-oriented personality who wants to work in a young and international team. Research Assistant and Research Fellow will be encouraged to present data at internal and external meetings and publish in peer-reviewed journals.

Applications should include full curriculum vitae, publication list, information on years of experience in research work, and names and contact information (e-mail and telephone numbers) of 3 references. Please also include a summary of your research experience and a brief paragraph on why you want to join the Sanda laboratory.

Please note that only shortlisted candidates will be contacted.

Dr Takaomi Sanda
Principal Investigator
Email: csitakao[at]nus.edu.sg
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Research Assistant (Bioinformatics & Software Development) – Jason Pitt Lab

The position of Research Assistant is immediately available in the laboratory of Dr Jason Pitt, which integrates cutting-edge data science techniques with biological expertise to facilitate novel discoveries in cancer genomics. Working closely with Dr Pitt, the shortlisted candidate will:

1)      Develop software solutions that allow cancer researchers to perform science at scale.
2)      Coordinate the aggregation, processing, and analysis of large genomic datasets.
3)      Document code and contribute to scientific manuscript writing.

Qualifications:

  • Bachelors’ or Masters’ in bioinformatics, computer science, genetics or related fields.
  • Strong Python programming skills and proficiency with Unix-based systems.
  • Working knowledge of databases (SQL, MySQL, noSQL, etc.) is an added advantage.
  • Experience analysing high-throughput biological data, particularly DNA sequencing is preferred.
  • Familiarity with high-performance and/or cloud computing is an added advantage.
  • Basic understanding of statistical inference.
  • Excellent written and spoken English.

Applications should include full curriculum vitae, publication list, and 2-3 reference letters. Please also include single page cover letter summarising your research experience, programmatic expertise, and why this position is of interest to you.

Dr. Jason J. Pitt
Special Fellow
Email: jason.j.pitt[at]nus.edu.sg

Research Associate - Bioinformatics Analyst

The position of Research Associate – jointly mentored by Drs. NG Siok Bian (NUHS & CSI) and Jason PITT (CSI) – is available immediately. Dr. Ng’s laboratory characterizes the molecular and pathological properties of EBV-associated lymphomas while the laboratory of Dr. Pitt applies data science techniques to identify critical features of cancer genomes. Working closely with both laboratories, the short-listed candidate will:

  1. Use high-throughput genomics data (e.g., WGS, WXS & RNA-seq) to elucidate the pathogenesis EBV-associated lymphomas.
  2. Coordinate the aggregation and harmonization of publicly available genomics datasets.
  3. Independently plan, analyze and interpret computational experiments.
  4. Document code and contribute to scientific manuscript writing.

Required qualifications:

  • Masters degree (at minimum) in bioinformatics, genetics, computer science or a related field.
  • Experience analysing high-throughput biological datasets, particularly DNA/RNA sequencing and microarray data.
  • Python programming skills and proficiency with Unix-based systems.
  • Understanding of and experience with statistical inference.
  • Excellent written and spoken English.

Preferred qualifications:

  • Familiarity with distributed computing systems (cluster, high-performance, and/or cloud computing).
  • Working knowledge of databases (SQL, MySQL, etc.).

Applications should include full curriculum vitae, publication list, and 2-3 reference letters. Please also include single page cover letter summarizing your research experience, programmatic expertise, and why this position is of interest to you.

Dr. Jason J. Pitt
Special Fellow
Email: jason.j.pitt[at]nus.edu.sg

Postdoctoral Fellow – Yvonne Tay Lab

A postdoctoral position is available immediately in Dr Yvonne Tay’s lab for a highly motivated Ph.D. or M.D graduate with a background in molecular or cellular biology, biochemistry or other related fields who is interested in deciphering regulatory RNA networks in the context of cancer (reviewed in Tay et al, Nature 2014; also see Tay et al, Nature 2008 and Tay et al, Cell 2011). The successful candidate will design and conduct experiments, analyse data, write papers and grants, mentor students, and compete for fellowships.

Qualifications:

  • A Ph.D. in cancer biology or related area.
  • Experience with in vivo animal models, particularly mice and/or zebrafish.
  • Expertise in RNA biology (including but not limited to microRNAs) is preferred.
  • Strong background and working knowledge of basic molecular and cellular biology techniques such as cell culture, cloning, real-time PCR and western blotting.
  • Experience with analyses of human clinical samples, RNA sequencing, RNA immunoprecipitation, mass spectrometry and/or CRISPR genome editing is highly desirable.
  • Ability to independently lead research projects and critically analyse data.
  • A proven track record in the form of publications in top international English language journals.
  • Ability to communicate in written and spoken English.

Applications should include full curriculum vitae, publication list, and names and contact information of 3 referees. Please also include a summary of your research experience.

Dr Yvonne Tay
Principal Investigator
Email: yvonnetay[at]nus.edu.sg
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