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Non-canonical activation of β-catenin by PRL-3 phosphatase in acute myeloid leukemia. (Oncogene, Oct 2018)

Chong PSY1, Zhou J1,2, Chooi JY2, Chan ZL1, Toh SHM1, Tan TZ1, Wee S3, Gunaratne J3,4, Zeng Q3, Chng WJ5,6,7. Author information 1Cancer Science Institute of Singapore, National University of Singapore, Singapore. 2Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 3Institute of Molecular and Cell Biology, A*STAR, Singapore. 4Department of Anatomy, Yong Loo Lin School of Medicine, National

Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features. (Nat Commun, Oct 2018)

Pitt JJ1,2, Riester M3, Zheng Y4, Yoshimatsu TF4, Sanni A5, Oluwasola O6, Veloso A3, Labrot E3, Wang S4,7, Odetunde A8, Ademola A9, Okedere B8, Mahan S3, Leary R3, Macomber M3, Ajani M6, Johnson RS3, Fitzgerald D1, Grundstad AJ1, Tuteja JH1, Khramtsova G4, Zhang J4, Sveen E4, Hwang B3, Clayton W4, Nkwodimmah C9, Famooto B9, Obasi E5, Aderoju V10, Oludara M10, Omodele F10, Akinyele O4, Adeoye A6, Ogundiran T9, Babalola C8,11, MacIsaac K3, Popoola A12, Morrissey MP3, Chen LS13, Wang J13, Olopade CO4, Falusi AG8, Winckler W3, Haase K14, Van Loo P14,15, Obafunwa J5, Papoutsakis D3, Ojengbede O16, Weber B3, Ibrahim N10, White KP17, Huo D18,19, Olopade OI20,21, Barretina

The c-MYC-BMI1 axis is essential for SETDB1-mediated breast tumourigenesis. (J Pathol, Sep 2018)

Xiao JF1, Sun QY1, Ding LW1, Chien W2, Liu XY1, Mayakonda A1, Jiang YY1, Loh XY1, Ran XB1, Doan NB3, Castor B3, Chia D4, Said JW3, Tan KT1, Yang H1, Fu XY1,5, Lin DC2, Koeffler HP1,2. Author information 1Cancer Science Institute of Singapore, National University of Singapore, Singapore. 2Division of Hematology/Oncology, Cedar-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA, USA. 3Department of Pathology, University of California, Los Angeles, CA, USA.

Aberrant Hyperediting of Myeloma Transcriptome by ADAR1 Confers Oncogenicity and is a Marker of Poor Prognosis. (Blood, Sep 2018)

Teoh PJ1, An O1, Chung TH1, Chooi JY1, Toh SHM1, Fan S2, Wang W3, Koh BTH4, Fullwood MJ5, Ooi MG6, de Mel S7, Soekojo CY6, Chen L8, Ng SB9, Yang H1, Chng WJ10. Author information 1 Cancer Science Institute of Singapore, National University of Singapore, Singapore. 2 Department of Pathology, National University Hospital, National University

Co-Activation of Super-Enhancer-Driven CCAT1 by TP63 and SOX2 Promotes Squamous Cancer Progression (Nat Commun, Sep 2018)

Jiang Y1, Jiang YY2, Xie JJ3, Mayakonda A1, Hazawa M4, Chen L5, Xiao JF1, Li CQ6, Huang ML1, Ding LW1, Sun QY1, Xu L1, Kanojia D1, Jeitany M1, Deng JW3, Liao LD7, Soukiasian HJ8, Berman BP9, Hao JJ10, Xu LY7, Li EM3, Wang MR10, Bi XG11, Lin DC12, Koeffler HP1,5,13. Author information 1Cancer Science Institute

Clinical Applications of Carbon Nanomaterials in Diagnostics and Therapy. (Adv Mater, Aug 2018)

Loh KP1, Ho D2,3,4,5, Chiu GNC6, Leong DT7, Pastorin G6, Chow EK8. Author Information 1Department of Chemistry and Centre for Advanced 2D Materials (CA2DM), National University of Singapore, Singapore, 117543, Singapore. 2Department of Biomedical Engineering, National University of Singapore, Singapore, 117583, Singapore. 3Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. 4Singapore Institute

RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair. (Cell Rep, Aug 2018)

Tay LS1, Krishnan V2, Sankar H1, Chong YL1, Chuang LSH1, Tan TZ1, Kolinjivadi AM1, Kappei D1, Ito Y3. Author information 1Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore. 2Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore. 3Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore. Abstract The Fanconi anemia (FA) pathway is a pivotal genome maintenance network

ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion. (Haematologica, Aug 2018)

Madan V1, Han L2, Hattori N3, Teoh WW2, Mayakonda A2, Sun QY2, Ding LW2, Binte Mohd Nordin H2, Lim SL2, Shyamsunder P2, Dakle P2, Sundaresan J2, Doan NB4, Sanada M5, Sato-Otsubo A6, Meggendorfer M7, Yang H2, Said JW4, Ogawa S6, Haferlach T7, Liang DC8, Shih LY9, Nakamaki T3, Wang QT10, Koeffler HP11. Author information 1

Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP). (Sci Trans Med, Aug 2018)

Rashid MBMA1,2, Toh TB1, Hooi L1, Silva A3, Zhang Y1, Tan PF4, Teh AL4, Karnani N4,5, Jha S1,5, Ho CM3,6,7, Chng WJ1,8, Ho D2,6,7,9,10,11, Chow EK12,2. Author information 1 Cancer Science Institute of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore. 2 Department of Pharmacology, Yong Loo Lin School

TIP60 represses activation of endogenous retroviral elements. (Nucleic Acids Res, Aug 2018)

Rajagopalan D1,2, Tirado-Magallanes R1, Bhatia SS1, Teo WS1, Sian S1, Hora S1,2, Lee KK1, Zhang Y1, Jadhav SP1, Wu Y3, Gan YH2, Karnani N2,3, Benoukraf T1, Jha S1,2. Author information 1 Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599. 2 Department of Biochemistry, Yong Loo Lin School of Medicine, National University of