French-Singaporean Symposium

RNA Biology applied to Leukemia research

 Paris, 12-13 April 2018



Gustave Roussy Université Paris Saclay IBENS RNA Biology Center CSI Singapore CSI Singapore




12 APRIL, 2018

Institut Gustave Roussy

Salle Pierre Denoix – 15th floor
Gustave Roussy Cancer Center
114 Rue Edouard Vaillant
94800 Villejuif, France

Clinical session

Time Speaker Title
9 am Daniel TENEN (CSI) /
Daniel GAUTHERET (Université Paris-Sud)
Welcome and Introduction to the RBC
9.30am Wee Joo CHNG (CSI) Oncogenic phosphatase, PRL-3, induced stem cell program in leukemic cells via LIN28 and Beta-Catenin which can be targeted for therapy
10.00 am Olivier HYRIEN (ENS) Developmental and cancer-associated plasticity of the DNA replication program.
10.30am Break
11.00am Chin Hin NG (NCIS) Recent Advancement in AML Treatment
11.30am Sudhakar JHA (CSI) TIP60-ing the balance towards cancer treatment


12.00 pm Lunch with IGR/Orsay Students


Basic Biology session

Time Speaker Title
2.00pm Camille LOBRY (GRCC) Identification and functional characterization of lncRNA in Acute Myeloid Leukemia 
2.30pm Polly CHEN (CSI) Understanding the Mechanisms for Fine-Tuning A-to-I RNA Editing in Cancer
3.00 pm Thomas MERCHER (GRCC) Modelling transcription factor networks from single cell RNA-seq data in a ETO2 fusion model
3.30 pm Break
4.00pm Daniel TENEN (CSI) Noncoding RNA Regulation of myeloid transcription factors, hematopoiesis, and leukemia
4.30 pm Vassili SOUMELIS (Institut Curie) Transcriptomics approaches to dissect human dendritic cell heterogeneity in infection and cancer
5 30 pm Round Table



13 APRIL, 2018

École Normale Supérieure
Salle Favard – Level 5 – room 513
Institut de Biologie de l’École Normale Supérieure (IBENS)
46 Rue d’Ulm

75005 Paris, France


Bioinformatics session

Time Speaker Title
9.15am Denis THIEFFRY (IBENS) Welcome address
9.30 am Touati BENOUKRAF (CSI) HybridSeek: An Integrative Structural Variant Discovery Tool Using Short and Long Read Sequencing Technologies
10.00 am Antonio RAUSELL (Imagine) Bionformatics methods for high-dimensional single-cell transcriptome analysis: from cell hierarchies to cell identity and cell state prediction at single-cell resolution
10.30 am Break
11.00am Morgane THOMAS-CHOLLIER (IBENS) Single-cell RNA-seq analysis pipelines using the Eoulsan Workflow engine
11.30am Daniel GAUTHERET (Université Paris-Sud) Finding novel RNA forms in cancer patients through hypothesis-free RNA-seq analysis: application to CMML
12.00pm Melissa FULLWOOD (CSI) Machine Learning for Prediction of Chromatin Interaction Alterations in Cancer

12.30 pm Lunch with ENS Students