Breast Cancer Awareness Month 2016

October is dedicated to breast cancer. Breast Cancer Awareness Month is an annual international health campaign that aims to increase awareness of breast cancer and raise funds for research into its cause, prevention, diagnosis, treatment and cure. For this month, CSI Singapore would like to debunk some myths shrouding breast cancer.

MYTH #1:

Men do not get breast cancer; it affects women only.


According to a study done in Singapore, men do get breast cancer, albeit rare. Nevertheless, men should also conduct periodic check themselves by self-examining their breasts in the shower and consult their doctors if they detect any changes.

Breast cancer in men is usually detected as a hard lump underneath the nipple and areola.  Men carry a higher mortality than women do, primarily because awareness among men is less and they are less likely to assume a lump is breast cancer, which can cause a delay in seeking treatment.

MYTH #2:

If the gene mutation BRCA1 or BRCA2 is detected in your DNA, you will definitely develop breast cancer.


The presence of BRCA1 or BRCA2 mutation is not a definite guarantee development of breast and/or ovarian cancer. However, women with these mutations are 5 times more likely to develop than women without such mutations.

MYTH #3:

Finding a lump in your breast means you have breast cancer.


Only a small percentage of lumps detected in the breast turns out to be cancerous. However, once a persistent lump or any changes is detected, it is important to consult the doctors for a clinical breast examination to determine the nature of the lump.

(Information courtesy of National Breast Cancer Foundation, Inc.)

In CSI Singapore, we have a team of researchers focusing on unravelling the causes of breast cancer and identifying potential therapeutic options. The Breast Cancer group comprises of scientists with distinct strengths focusing on different aspects of breast cancer progression. Here, we showcase some of our significant research work and discoveries in the fight against breast cancer.

Peter Lobie_PIpage_on Senior Principal Investigator, Prof Peter Lobie and his group study how hormones and secreted proteins have the potential to initiate the progression of cancer, particularly breast and endometrial carcinoma.


Principal Investigator, Dr Pieter Eichhorn, is particularly interested in the ubiquitination of proteins and how this could affect cancer progression. pieter_eichhorn_on


Teh6May_on Prof Teh Bin Tean, Senior Principal Investigator at CSI, together with his team, concentrates their research on RARA mutations through molecular dynamic and modelling studies. Their studies will provide insights into the molecular pathogenesis of breast fibroepithelial tumors, with potential clinical implications.


Senior Principal Investigator and ocologist, Dr Lee Soo Chin’s laboratory emphasizes on the study of pharmacogenetics and genomics in breast cancer. Lee6May_on


Alan-Prem-KUMAR Dr Alan Prem Kumar, Principal Associate at CSI Singapore, recently had a significant breakthrough in his research on breast cancer, where his team uncovered the new role of DP103 protein in promoting tumor metastasis in breast cancer patients.

Take charge of your health through regular self-examinations, clinical check-ups and routine mammogram screenings. You can also show your support to the institute’s research efforts by making a contribution here.