Publication Highlights

Selected publications: Jun – Dec 2014

    1. Sheng W, Yang F, Zhou Y, Yang H, Low PY, Kemeny DM, Tan P, Moh A, Kaplan MH, Zhang Y, Fu XY. STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation. Cell Res. 2014 Dec; 24(12):1387-402.
    2. Wang X, Low XC, Hou W, Abdullah LN, Toh TB, Mohd Abdul Rashid M, Ho D, Chow EK. Epirubicin-AdsorbedNanodiamonds Kill Chemoresistant Hepatic Cancer Stem Cells. ACS Nano. 2014 Dec; epub.
    3. Ng SB, Ohshima K, Selvarajan V, Huang G, Choo SN, Miyoshi H, Wang S, Chua HC, Yeoh A, Quah TC, Koh LP, Tan PL, Chng WJ. Prognostic implication of morphology, cyclinE2 and proliferation in EBV-associated T/NK lymphoproliferative disease in non-immunocompromised hosts. Orphanet J Rare Dis. 2014 Dec; 9(1):165.
    4. Sun QY, Ding LW, Xiao JF, Chien W, Lim SL, Hattori N, Goodglick L, Chia D, Mah V, Alavi M, Kim SR, Doan NB, Said JW, Loh XY, Xu L, Liu LZ, Yang H, Hayano T, Shi S, Xie D, Lin DC, Koeffler HP. SETDB1 accelerates tumorigenesis by regulating WNT signaling pathway. J Pathol. 2014 Nov; epub.
    5. Garg M, Okamoto R, Nagata Y, Kanojia D, Venkatesan S, M T A, Braunstein GD, Said JW, Doan NB, Ho Q, Akagi T, Gery S, Liu LZ, Tong Tan K, Joo Chng W, Yang H, Ogawa S, Phillip Koeffler H. Establishment and Characterization of Novel Human Primary and Metastatic Anaplastic Thyroid Cancer Cell Lines and Their Genomic Evolution Over a Year as a Primagraft. J Clin Endocrinol Metab. 2014 Nov; epub.
    6. Sapari NS, Elahi E, Wu M, Loh M, Ng HK, Han X, Yap HL, Klemm TP, Pang B, Benoukraf T, Teo YY, Iacopetta B, Lee SC, Soong R. Feasibility of Low-Throughput Next Generation Sequencing for Germline DNA Screening. Clin Chem. 2014 Oct; epub.
    7. Tan TZ, Miow QH, Miki Y, Noda T, Mori S, Huang RY, Thiery JP. Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients. EMBO Mol Med. 2014 Sep; 6(10):1279-93.
    8. Pandey V, Wu ZS, Zhang M, Li R, Zhang J, Zhu T, Lobie PE. Trefoil factor 3 promotes metastatic seeding and predicts poor survival outcome of patients with mammary carcinoma. Breast Cancer Res. 2014 Sepl 16(5):429.
    9. Lin DC, Meng X, Hazawa M, Nagata Y, Varela AM, Xu L, Sato Y, Liu LZ, Ding LW, Sharma A, Goh BC, Lee SC, Petersson BF, Yu FG, Macary P, Oo MZ, Ha CS, Yang H, Ogawa S, Loh KS, Koeffler HP. The genomic landscape of nasopharyngeal carcinoma. Nat Genet. 2014 Aug; 46(8):866-71.
    10. Shin EM, Sin Hay H, Lee MH, Goh JN, Tan TZ, Sen YP, Lim SW, Yousef EM, Ong HT, Thike AA, Kong X, Wu Z, Mendoz E, Sun W, Salto-Tellez M, Lim CT, Lobie PE, Lim YP, Yap CT, Zeng Q, Sethi G, Lee MB, Tan P, Goh BC, Miller LD, Thiery JP, Zhu T, Gaboury L, Tan PH, Hui KM, Yip GW, Miyamoto S, Kumar AP, Tergaonkar V. DEAD-box helicase DP103 defines metastatic potential of human breast cancers. J Clin Invest. 2014 Aug; 124(9):3807-24.
    11. Wang CQ, Krishnan V, Tay LS, Chin DW, Koh CP, Chooi JY, Nah GS, Du L, Jacob B, Yamashita N, Lai SK, Tan TZ, Mori S, Tanuichi I, Tergaonkar V, Ito Y, Osato M. Disruption of Runx1 and Runx3 Leads to Bone Marrow Failure and Leukemia Predisposition due to Transcriptional and DNA Repair Defects. Cell Rep. 2014 Jul; 8(3):767-82.
    12. Hor YT, Voon DC, Koo JK, Wang H, Lau WM, Ashktorab H, Chan SL, Ito Y. A Role for RUNX3 in Inflammation-Induced Expression of IL23A in Gastric Epithelial Cells. Cell Rep. 2014 Jul; 8(1):50-8.
    13. Osato M. An unsung runt 6e isoform for HSC expansion. Blood. 2014 Jun; 123(24):3684-6.
    14. Chong PS, Zhou J, Cheong LL, Liu SC, Qian J, Guo T, Sze SK, Zeng Q, Chng WJ. LEO1 is regulated by PRL-3 and mediates its oncogenic properties in Acute Myeloid Leukemia. Cancer Res. 2014 Jun; 74(11):3043-53.