CSI Singapore Congratulates Winners at the 9th NCIS Annual Research Meeting (NCAM 2022)

August 30, 2022

Hosted by the National University Cancer Institute, Singapore (NCIS), the 9th NCIS Annual Research Meeting (NCAM) had its meeting between...

Read More

Aug 30, 2022 C K Sangamitha 0 comments
A Genomic-augmented Multivariate Prognostic Model for the Survival of Natural-killer/T-cell Lymphoma Patients from an International Cohort (Am J Hematol, Jun 2022)

August 15, 2022

With lowering costs of sequencing and genetic profiling techniques, genetic drivers can now be detected readily in tumors but current...

Read More

Aug 15, 2022 C K Sangamitha 0 comments
A Degradative to Secretory Autophagy Switch Mediates Mitochondria Clearance in the Absence of the mATG8-conjugation Machinery (Nat Commun., Jun 2022)

August 15, 2022

PINK1-Parkin mediated mitophagy, a selective form of autophagy, represents one of the most important mechanisms in mitochondrial quality control (MQC)...

Read More

Aug 15, 2022 C K Sangamitha 0 comments
SETDB1 Acts as a Topological Accessory to Cohesin via an H3K9me3-independent, Genomic Shunt for Regulating Cell Fates (Nucleic Acids Res, Jul 2022)

August 10, 2022

SETDB1 is a key regulator of lineage-specific genes and endogenous retroviral elements (ERVs) through its deposition of repressive H3K9me3 mark.

Read More

Aug 10, 2022 C K Sangamitha 0 comments
Congratulations to the Graduating Class of 2022!

August 10, 2022

CSI Singapore would like to extend its heartiest congratulations to the graduates of the PhD Graduate Program in Cancer Biology!

Read More

Aug 10, 2022 C K Sangamitha 0 comments
[Review] Integration of Genomic Biology Into Therapeutic Strategies of Gastric Cancer Peritoneal Metastasis (J Clin Oncol, June 2022)

July 25, 2022

The peritoneum is a common site of metastasis in advanced gastric cancer (GC). Diagnostic laparoscopy is now routinely performed as...

Read More

Jul 25, 2022 C K Sangamitha 0 comments
Bioorthogonal Catalysis for Treatment of Solid Tumors Using Thermostable, Self-Assembling, Single Enzyme Nanoparticles and Natural Product Conversion with Indole-3-acetic Acid (ACS Nano., June 2022)

July 25, 2022

Bioorthogonal catalysis (BC) generates chemical reactions not present in normal physiology for the purpose of disease treatment. Because BC catalytically...

Read More

Jul 25, 2022 C K Sangamitha 0 comments
Identification of Mechanism of Cancer-cell-specific Reactivation of hTERT Offers Therapeutic Opportunities for Blocking Telomerase Specifically in Human Colorectal Cancer (Nucleic Acids Res., June 2022)

July 22, 2022

Transcriptional reactivation of hTERT is the limiting step in tumorigenesis. While mutations in hTERT promoter present in 19% of cancers...

Read More

Jul 22, 2022 C K Sangamitha 0 comments
CSI Singapore Principal Investigators Part of a Collaborative Effort to Secure a $25M NMRC Collaborative Grant to Tackle Liver Cancer

June 21, 2022

CSI Singapore would like to congratulate its Principal Investigators, namely Prof. Patrick Tan, Assoc. Prof. Edward Chow and Dr. Tam...

Read More

Jun 21, 2022 C K Sangamitha 0 comments
Congratulations to Ms. Xu Jingru, a CSI PhD student on receiving the Materials Research Society (MRS) 2022 NM05 Symposium Best Student Oral Presentation Award!

June 14, 2022

Held in Honolulu, Hawaii between May 8 – 13, Ms. Xu Jingru presented at the NM05 Symposium, which focuses on...

Read More

Jun 14, 2022 C K Sangamitha 0 comments
Hepatocellular Carcinoma Organoid Co-cultures Mimic Angiocrine Crosstalk to Generate Inflammatory Tumor Microenvironment (Biomaterials, May 22)

June 13, 2022

Despite approvals of several therapeutics to treat advanced HCC in the past few years, the impact of anti-angiogenic treatment on...

Read More

Jun 13, 2022 C K Sangamitha 0 comments
Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer (Cancer Res, May 22)

June 13, 2022

Mutations in the DNA mismatch repair gene MSH2 are causative of microsatellite instability (MSI) in multiple cancers. Here, we discovered...

Read More

Jun 13, 2022 C K Sangamitha 0 comments
Demethylation and Up-regulation of an Oncogene After Hypomethylating Therapy (N Engl J Med, May 22)

June 13, 2022

Although hypomethylating agents are currently used to treat patients with cancer, whether they can also reactivate and up-regulate oncogenes is...

Read More

Jun 13, 2022 C K Sangamitha 0 comments
Search
Generic selectors
Exact matches only
Search in title
Search in content
Search in posts
Search in pages
Filter by Categories
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
Associate Investigators
Awards & Achievements
Biosketch
Events
Facility Heads
Graduate Programme
Journal Clubs
Lab Members
Latest Happenings
Media
Newsletter
Principal Investigators
Prof Daniel G. TENEN Program Members
Prof GOH Boon Cher Program Members
Publication
Research
Research
RNA Biology Center
Senior Principal Investigators
Special Fellows
The Team
Uncategorized
Visits
Year 2021
Year 2022